Lee M. Hoffart

Pennsylvania State University — United States

Chemistry · Physical Sciences

14h-index1.7kcitations15works0.02yr avg
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Research Topics

Metal-Catalyzed Oxygenation Mechanisms(12), Heme Oxygenase-1 and Carbon Monoxide(4), Photosynthetic Processes and Mechanisms(3), Microbial metabolism and enzyme function(3), Pharmacogenetics and Drug Metabolism(2)

Publications15 total

Evidence for the slow reaction of hypoxia‐inducible factor prolyl hydroxylase 2 with oxygen
FEBS Journal·2010· 89 citedOpen Access
SufR Coordinates Two [4Fe-4S]2+, 1+ Clusters and Functions as a Transcriptional Repressor of the sufBCDS Operon and an Autoregulator of sufR in Cyanobacteria
Journal of Biological Chemistry·2007· 75 citedOpen Access
A Manganese(IV)/Iron(IV) Intermediate in Assembly of the Manganese(IV)/Iron(III) Cofactor of <i>Chlamydia trachomatis</i> Ribonucleotide Reductase
Biochemistry·2007· 82 citedOpen Access
A Manganese(IV)/Iron(III) Cofactor in <i>Chlamydia trachomatis</i> Ribonucleotide Reductase
Science·2007· 200 cited
Reaction of Cytochrome P450<sub>BM3</sub> and Peroxynitrite Yields Nitrosyl Complex
Journal of the American Chemical Society·2007· 29 cited
Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase
Proceedings of the National Academy of Sciences·2006· 323 citedOpen Access
Evidence for Basic Ferryls in Cytochromes P450
Journal of the American Chemical Society·2006· 99 cited
Evidence for Two Ferryl Species in Chloroperoxidase Compound II
Journal of the American Chemical Society·2006· 88 cited
Evidence for C–H cleavage by an iron–superoxide complex in the glycol cleavage reaction catalyzed by <i>myo</i> -inositol oxygenase
Proceedings of the National Academy of Sciences·2006· 117 citedOpen Access
Oxygen Activation by a Mixed-Valent, Diiron(II/III) Cluster in the Glycol Cleavage Reaction Catalyzed by <i>myo</i>-Inositol Oxygenase
Biochemistry·2006· 66 cited
A Coupled Dinuclear Iron Cluster that Is Perturbed by Substrate Binding in <i>myo</i>-Inositol Oxygenase
Biochemistry·2006· 62 cited
Mechanism of Taurine: α‐Ketoglutarate Dioxygenase (TauD) from Escherichia coli
ChemInform·2005
Mechanism of Taurine: α‐Ketoglutarate Dioxygenase (TauD) from <i>Escherichia coli</i>
European Journal of Inorganic Chemistry·2005· 195 cited
Kinetic Dissection of the Catalytic Mechanism of Taurine:α-Ketoglutarate Dioxygenase (TauD) from <i>Escherichia coli</i>
Biochemistry·2005· 193 cited
<i>Escherichia coli</i> Quinolinate Synthetase Does Indeed Harbor a [4Fe-4S] Cluster
Journal of the American Chemical Society·2005· 50 cited

Frequent Co-authors

Carsten Krebs(15), J. Martin Bollinger(10), Eric W. Barr(7), Gang Xing(4), John C. Price(3), Yinghui Diao(3), K. Sandeep Prabhu(3), Ryan J. Arner(3), C. Channa Reddy(3), Rachel K. Behan(3), Kari L. Stone(3), Michael T. Green(3), Wei Jiang(2), Robert B. Guyer(1), Danny Yun(1), Lana Saleh(1), Monique-Anne Maslak(1), Emily Flashman(1), Refaat B. Hamed(1), Christopher J. Schofield(1)