Ramesh A. Shivdasani

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

87h-index27.4kcitations270works7.42yr avg
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Research Topics

Digestive system and related health(51), Epigenetics and DNA Methylation(47), Platelet Disorders and Treatments(45), Cancer Cells and Metastasis(43), Cancer-related gene regulation(26)

Publications270 total

Epigenetic Gatekeeping of Intestinal Stem Cell Transformation
2026Open Access
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Gastroenterology·2025
Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell
Cell stem cell·2025· 6 cited
Remodelling the Colon With Ileal Properties to Treat Short Bowel Syndrome
Gastroenterology·2025· 2 cited
Epigenetic fluidity meets phenotypic malleability in intestinal epithelial cells
Cell chemical biology·2025
Niche-driven phenotypic plasticity and cis-regulatory dynamics of a revised model for intestinal secretory differentiation
2025Open Access
Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium
2025· 1 citedOpen Access
Crypt density and recruited enhancers underlie intestinal tumour initiation
Nature·2025· 12 citedOpen Access
Epigenetic investigation of multifocal small intestinal neuroendocrine tumours reveals accelerated ageing of tumours and epigenetic alteration of metabolic genes
2024Open Access
Short-term post-fast refeeding enhances intestinal stemness via polyamines
Nature·2024· 45 citedOpen Access
Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
Cell stem cell·2024· 16 citedOpen Access
A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin
Nature Communications·2024· 7 citedOpen Access
Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
2024· 7 citedOpen Access
Role of PDGFRA+ cells and a CD55+ PDGFRALo fraction in the gastric mesenchymal niche
Nature Communications·2023· 14 citedOpen Access
Cochlear organoids reveal transcriptional programs of postnatal hair cell differentiation from supporting cells
Cell Reports·2023· 14 citedOpen Access
Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche
Cell stem cell·2023· 78 citedOpen Access
Supplementary Figures S1-S5 from Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype
2023Open Access
Supplementary Figures S1-S5 from Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype
2023Open Access
Data from Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype
2023Open Access
Supplementary Tables S1-S5 from Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype
2023Open Access
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Frequent Co-authors

Stuart H. Orkin(8), Joseph E. Italiano(7), Adam J. Bass(6), Shuji Ogino(6), Matthew Meyerson(6), Juliet Philips(5), Josep Tabernero(4), William C. Hahn(4), John H. Hartwig(4), Alex H. Ramos(3), Ellen Freed(3), Jordi Barretina(3), Jennifer A. Chan(3), Charles S. Fuchs(3), Michael P. Verzi(3), Harald Schulze(3), Patrick Lécine(3), Henry W. Long(3), Matthew H. Kulke(3), Assieh Saadatpour(3)