Guangrong Zheng

Kunming Medical University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index5.8kcitations234works4.62yr avg
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Research Topics

Protein Degradation and Inhibitors(70), Ubiquitin and proteasome pathways(35), Receptor Mechanisms and Signaling(35), Nicotinic Acetylcholine Receptors Study(35), Multiple Myeloma Research and Treatments(32)

Publications234 total

Tumor cell membrane camouflaged liposomal pharmaceuticals for cascade catalysis‐driven redox modulation and synergistic ROS/RNS antitumor therapy
View·2026Open Access
Bacterial Cytochrome P450 for Oxidative Halogenated Biaryl Coupling
ACS Catalysis·2025
Assembled Gold Superstructure Triggered Synergistic Apoptosis/Ferroptosis via Combined Photo-Enzyme Therapy
ACS Applied Materials & Interfaces·2025
Impact of contrast enhancement boost and super-resolution deep learning reconstruction on pediatric congenital heart disease CTA scans: ultra-low contrast dose
BMC Medical Imaging·2025Open Access
First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies
Journal of Hematology & Oncology·2025· 3 citedOpen Access
Staged Low‐Frequency Ultrasound Synergized with Composite Hydrogel to Achieve “Rapid Antimicrobial‐Ordered Regeneration” of Infected Wounds
Advanced Healthcare Materials·2025
Screening of an antibacterial peptide WRIIIKK with antioxidative properties and its application in wound healing and keratitis treatment
Applied Materials Today·2025
Harnessing Chimeric Degrader Technologies for Antimicrobial Innovation
Journal of Medicinal Chemistry·2025· 2 cited
Quiescent OXPHOS-High Triple-Negative Breast Cancer Cells That Persist After Chemotherapy Depend on BCL-XL for Survival
Cells·2025Open Access
Dual Targeting of IKKβ and NR4A1 for AML Therapy
2025Open Access
Spatiotemporally Ultrasound-Activatable Self-Amplifying Biomimetic Liposomes for Imaging-Guided Synergistic Cancer Sonodynamic Chemotherapy
Nano Letters·2025
Unveiling BCL-xL-specific PROTAC Efficiency and Dissociation Mechanisms Using Native Mass Spectrometry
2025· 1 cited
Discovery of CRBN-recruiting PROTAC degraders of the METTL3-METTL14 complex
Medicinal Chemistry Research·2025· 1 citedOpen Access
Discovery of Dual BCL-xL/BCL-w Degraders by Exploiting the Bis(sulfonyl)benzene Ring of ABT-263 as a Linkage Vector
Journal of Medicinal Chemistry·2025· 1 cited
Quiescent OXPHOS-high triple-negative breast cancer cells that persist after chemotherapy depend on BCL-XL for survival
2025· 1 citedOpen Access
Nano-TPD: Using nanoparticle-based systems to improve the delivery and therapeutic effect of targeted protein degraders
Medicinal Chemistry Research·2025· 2 cited
Bacteria-based drug-loaded mesoporous silica nanoparticles for synergistic FUAS of breast cancer
Cancer Nanotechnology·2025· 2 citedOpen Access
Targeting Lineage-Specific Functions of NR4A1 for Cancer Immunotherapy
International Journal of Molecular Sciences·2025· 4 citedOpen Access
Abstract CT063: First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies (NCT04886622)
Cancer Research·2025· 4 cited
Abstract LB419: HDAC8 over-expression promotes drug resistance and alters chromatin architecture in melanoma cells
Cancer Research·2025
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Frequent Co-authors

Daohong Zhou(28), Xuan Zhang(23), Peiyi Zhang(15), Dongwen Lv(13), Xingui Liu(13), Sajid Khan(12), Dinesh Thummuri(12), Yaxia Yuan(12), Linda P. Dwoskin(12), Yonghan He(11), Peter A. Crooks(11), Vivekananda Budamagunta(7), J Wiegand(6), Robert Hromas(6), Wanyi Hu(6), Weizhou Zhang(5), Nan Hua(5), Agripina G. Deaciuc(5), Jing Pei(4), Judith Campisi(4)