Duraiswamy Navaneetham

Medicine · Health Sciences

16h-index1.2kcitations28works0.02yr avg
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Research Topics

Coagulation, Bradykinin, Polyphosphates, and Angioedema(13), Blood Coagulation and Thrombosis Mechanisms(8), Myasthenia Gravis and Thymoma(7), Protease and Inhibitor Mechanisms(5), Peripheral Neuropathies and Disorders(5)

Publications28 total

Organization for rare diseases India (ORDI) – addressing the challenges and opportunities for the Indian rare diseases' community
Genetics Research·2014· 54 citedOpen Access
P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor
The Journal of Biochemistry·2012· 10 citedOpen Access
The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis
Blood·2012· 49 citedOpen Access
The Role of Factor XIa (FXIa) Catalytic Domain Exosite Residues in Substrate Catalysis and Inhibition by the Kunitz Protease Inhibitor Domain of Protease Nexin 2
Journal of Biological Chemistry·2011· 7 citedOpen Access
Structural and Mutational Analysis of Canonical Loop Residues In Protease Nexin 2 Involved In Factor XIa and Trypsin Inhibition.
Blood·2010
Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with Mesotrypsin
Journal of Biological Chemistry·2010· 47 citedOpen Access
Mechanisms and specificity of factor XIa and trypsin inhibition by protease nexin 2 and basic pancreatic trypsin inhibitor
The Journal of Biochemistry·2010· 24 citedOpen Access
The Amyloid Precursor Protein/Protease Nexin 2 Kunitz Inhibitor Domain Is a Highly Specific Substrate of Mesotrypsin
Journal of Biological Chemistry·2009· 42 citedOpen Access
The Role of the P1 Residue of Protease Nexin 2 and Basic Pancreatic Trypsin Inhibitor in the Mechanism of Factor XIa Inhibition.
Blood·2008
Retraction: Thrombin activation of factor XI on activated platelets requires the interaction of factor XI and platelet glycoprotein Ibα with thrombin anion-binding exosites I and II, respectively. VOLUME 278 (2003) PAGES 48112-48119
Journal of Biological Chemistry·2007· 2 citedOpen Access
Macromolecular Substrate-Binding Exosites on Both the Heavy and Light Chains of Factor XIa Mediate the Formation of the Michaelis Complex Required for Factor IX-Activation
Biochemistry·2007· 12 cited
Factor IX Substrate Binding Exosite on the Light Chain of Factor Xia.
Blood·2005· 1 cited
Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2
Journal of Biological Chemistry·2005· 72 citedOpen Access
Thrombin Activation of Factor XI on Activated Platelets Requires the Interaction of Factor XI and Platelet Glycoprotein Ibα with Thrombin Anion-binding Exosites I and II, Respectively
Journal of Biological Chemistry·2003· 87 citedOpen Access
Human Bronchial Epithelial and Endothelial Cells Express α7 Nicotinic Acetylcholine Receptors
Molecular Pharmacology·2001· 217 cited
Human thymuses express incomplete sets of muscle acetylcholine receptor subunit transcripts that seldom include the ? subunit
Muscle & Nerve·2001· 36 cited
Neuronal nicotinic receptors in non-neuronal cells: new mediators of tobacco toxicity?
European Journal of Pharmacology·2000· 171 cited
Anti-Acetylcholine Receptor CD4+ T Cells in Myasthenia Gravis: Epitope repertoire and T cell receptor gene usage
2000· 2 cited
TCR-Vβ Usage in the Thymus and Blood of Myasthenia Gravis Patients
Journal of Autoimmunity·1998· 19 cited
Human and Rodent Bronchial Epithelial Cells Express Functional Nicotinic Acetylcholine Receptors
Molecular Pharmacology·1998· 232 cited
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Frequent Co-authors

Bianca M. Conti‐Fine(12), Peter N. Walsh(12), Dipali Sinha(8), Raghavan Raju(7), James F. Howard(7), Arno D.J. Maus(3), Robert M. Horton(3), Bobbi L. Hoppe(3), Edna F. R. Pereira(2), Peter Karachunski(2), Edson X. Albuquerque(2), Thomas H. Yun(2), Frank A. Baglia(2), Timothy Myles(2), Lawrence Leung(2), Wenman Wu(2), Hongbo Li(2), Ronald F. Tuma(2), Moh’d A. Salameh(2), Evette S. Radisky(2)