Winfried S. Wels

Goethe University Frankfurt — Germany

Medicine · Health Sciences

61h-index14.4kcitations280works6.92yr avg
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Research Topics

CAR-T cell therapy research(153), Monoclonal and Polyclonal Antibodies Research(87), Immune Cell Function and Interaction(87), Immunotherapy and Immune Responses(48), Toxin Mechanisms and Immunotoxins(45)

Publications275 total

IMMU-15. Local CAR-NK cell therapy in combination with systemic checkpoint inhibition induces anti-tumor responses even in distant tumor locations in an immunocompetent glioblastoma mouse model
Neuro-Oncology·2025Open Access
P08.08.B CAR-NK CELL THERAPY COMBINED WITH CHECKPOINT INHIBITION INDUCES A DISTANT ANTI-TUMOR RESPONSE IN AN IMMUNOCOMPETENT GLIOBLASTOMA MOUSE MODEL
Neuro-Oncology·2025Open Access
P18.15.A IMMUNOCOMPETENT GLIOBLASTOMA ORGANOIDS FOR PERSONALIZED IMMUNE PROFILING
Neuro-Oncology·2025Open Access
P08.23.A CAR-ENGINEERED PRIMARY NK CELLS SHOW PROMISING EFFECTS AS TARGETED THERAPY AGAINST EGFR-POSITIVE GLIOBLASTOMA
Neuro-Oncology·2025Open Access
Precision targeting of rhabdomyosarcoma by combining primary CAR NK cells and radiotherapy
Journal for ImmunoTherapy of Cancer·2025· 6 citedOpen Access
In vitro and in vivo comparison of VHH- and scFv-based CLEC12A-chimeric antigen receptor-natural killer cells against acute myeloid leukemia
Klinische Pädiatrie·2025
Dual-CAR NK cells targeting PD-L1 and ErbB2/HER2 eliminate solid tumor cells and prevent immune escape due to antigen loss
Cytotherapy·2025· 1 cited
ErbB2/HER2-targeted CAR-NK cells eliminate breast cancer cells in an organoid model that recapitulates tumor progression
Molecular Therapy·2025· 4 citedOpen Access
Chimeric antigen receptor NK-92 cell function is modulated by HLA class I expression of target cells
iScience·2025· 2 citedOpen Access
CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma
British Journal of Cancer·2025· 10 citedOpen Access
CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma
Frontiers in Immunology·2025· 8 citedOpen Access
Engineered Natural Killer Cell Lines and Their Application for Cancer Immunotherapy
2024
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial
UNC Libraries·2024· 1 citedOpen Access
256 Dual targeting of PD-L1 and ErbB2 by CAR-NK cells enables specific elimination of solid tumor cells and overcomes immune escape via antigen loss
Regular and Young Investigator Award Abstracts·2024· 1 citedOpen Access
CTIM-04. MODULATION OF THE INTRATUMORAL IMMUNE MICROENVIRONMENT BY LOCAL THERAPY WITH NATURAL KILLER CELLS ENGINEERED WITH A HER2-TARGETED CHIMERIC ANTIGEN RECEPTOR IN COMBINATION WITH SYSTEMIC ANTI-PD-1 CHECKPOINT INHIBITION IN PATIENTS WITH RECURRENT GLIOBLASTOMA
Neuro-Oncology·2024Open Access
Empowering Natural Killer Cells to Combat Acute Myeloid Leukemia: Perspective on CAR-NK Cell Therapy
Transfusion Medicine and Hemotherapy·2024· 1 citedOpen Access
P12.04.A CAR-ENGINEERED PRIMARY NK CELLS SHOW PROMISING EFFECTS AS TARGETED THERAPY AGAINST EGFR-POSITIVE GLIOBLASTOMA
Neuro-Oncology·2024Open Access
KS05.5.A REPETITIVE INTRACRANIAL INJECTION OF NATURAL KILLER CELLS ENGINEERED WITH A HER2-TARGETED CHIMERIC ANTIGEN RECEPTOR ALONE AND IN COMBINATION WITH SYSTEMIC ANTI-PD-1 CHECKPOINT INHIBITION IN PATIENTS WITH RECURRENT GLIOBLASTOMA
Neuro-Oncology·2024Open Access
Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies
Frontiers in Immunology·2024· 4 citedOpen Access
CAR-MEDIATED TARGETING OF NK CELLS OVERCOMES TUMOR IMMUNE ESCAPE CAUSED BY ICAM-1 DOWNREGULATION
Cytotherapy·2024
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Frequent Co-authors

Torsten Tonn(13), Congcong Zhang(10), Nabil Ahmed(8), Gianpietro Dotti(7), Stephen Gottschalk(7), Hans Klingemann(7), Meenakshi Hegde(6), Helen E. Heslop(6), Christoph Uherek(6), Kurt Schönfeld(5), Bernd Groner(5), Vita S. Brawley(4), John Hicks(4), Cliona M. Rooney(4), Malcolm K. Brenner(4), Tiara T. Byrd(4), Michael C. Burger(4), Paulina Nowakowska(4), Sarah Oelsner(4), A Romański(4)