Graham Duddy

The Francis Crick Institute — United Kingdom

Immunology and Microbiology · Life Sciences

12h-index2.4kcitations31works9.02yr avg
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Research Topics

Immune Cell Function and Interaction(6), Helicobacter pylori-related gastroenterology studies(4), Veterinary medicine and infectious diseases(4), MicroRNA in disease regulation(3), Parkinson's Disease Mechanisms and Treatments(3)

Publications31 total

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
Nature·2025· 25 citedOpen Access
Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation
Nature Communications·2024· 10 citedOpen Access
Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations
Genome Medicine·2024· 3 citedOpen Access
Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines
Scientific Reports·2024· 6 citedOpen Access
Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human <i>MIR96</i> mutations
2024· 1 citedOpen Access
Donor template delivery by recombinant adeno-associated virus for the production of knock-in mice
BMC Biology·2024· 9 citedOpen Access
Epi-microRNA mediated metabolic reprogramming ensures affinity maturation
2023· 4 citedOpen Access
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
BMC Biology·2023· 18 citedOpen Access
Impact of Essential Genes on the Success of Genome Editing Experiments Generating 3,313 New Genetically Engineered Mouse Lines
2021· 5 citedOpen Access
Tumors induce de novo steroid biosynthesis in T cells to evade immunity
Nature Communications·2020· 323 citedOpen Access
Helicobacter pylori infection in shepherds, sheep and sheep-dogs
SHILAP Revista de lepidopterología·2020· 4 citedOpen Access
Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation
Cell·2019· 198 citedOpen Access
Tumors induce <i>de novo</i> steroid biosynthesis in T cells to evade immunity
2018· 2 citedOpen Access
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome
Nature Communications·2018· 208 citedOpen Access
Genome-wide CRISPR screens in T helper cells reveal pervasive cross-talk between activation and differentiation
2017· 3 citedOpen Access
Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors
Biochemical Journal·2016· 178 citedOpen Access
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
eLife·2016· 1.0k citedOpen Access
Author response: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
2016· 12 citedOpen Access
ASK2 mRNA levels increase in the spinal cord of 4-week diabetic mice compared with controls.
Figshare·2015Open Access
Targeting Apoptosis Signalling Kinase-1 (ASK-1) Does Not Prevent the Development of Neuropathy in Streptozotocin-Induced Diabetic Mice
PLoS ONE·2014· 4 citedOpen Access
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Frequent Co-authors

David J. Adams(6), Jhuma Pramanik(4), Xi Chen(4), Edward J. Ryder(4), Sarah A. Teichmann(4), Brendan Doe(4), Francesca Tonelli(3), Genta Ito(3), Marco A. S. Baptista(3), Alastair D. Reith(3), Dario R. Alessi(3), Evelyn Grau(3), Ramiro Ramírez‐Solis(3), Joanna Bottomley(3), Diane Gleeson(3), Kosuke Yusa(3), Robert E. Braun(3), Steve D. M. Brown(3), Mary E. Dickinson(3), Yann Hérault(3)