D. Fraughen

Royal College of Surgeons in Ireland — Ireland

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index165citations47works0.62yr avg
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Research Topics

Protease and Inhibitor Mechanisms(25), Peptidase Inhibition and Analysis(11), Blood Coagulation and Thrombosis Mechanisms(9), COVID-19 Clinical Research Studies(4), Liver Disease Diagnosis and Treatment(3)

Publications47 total

Severe Alpha-1 antitrypsin deficiency detected via Family Screening— Are never-smokers disease-free?
2025
Late Breaking Abstract - Real-world evidence for severe Alpha-1 Antitrypsin Deficiency: Life-years gained for augmentation therapy versus standard care
2025
Seasonal Changes in Circulating Alpha-1 Antitrypsin Are Altered by Sex and Genetic Deficiency
American Journal of Respiratory and Critical Care Medicine·2025
Longitudinal Analysis of Alpha-1 Antitrypsin Patients on Augmentation Therapy
American Journal of Respiratory and Critical Care Medicine·2025
Alpha-1 Antitrypsin – A Prognostic Factor in Acute Respiratory Distress Syndrome
American Journal of Respiratory and Critical Care Medicine·2025
Family Screening in Alpha-1 Antitrypsin Deficiency – Is It Enough?
American Journal of Respiratory and Critical Care Medicine·2025
Moderate Deficiency of Alpha-1 Antitrypsin – What's the Risk in SS Compared to MZ AATD?
American Journal of Respiratory and Critical Care Medicine·2025
Sex Hormone Abnormalities Disrupt Circulating Alpha-1 Antitrypsin
American Journal of Respiratory and Critical Care Medicine·2025· 1 cited
Optimising bronchoalveolar lavage: lessons from alpha-1 antitrypsin deficiency
Thorax·2024· 3 citedOpen Access
Effectiveness of hybrid simulation training on medical student performance in whole-task consultation of cardiac patients: The ASSIMILATE EXCELLENCE randomized waitlist-controlled trial
Advances in Simulation·2024· 3 citedOpen Access
The impact of mannose-binding lectin (MBL) deficiency on bronchiectasis in Alpha-1 Antitrypsin Deficiency
2024
Delayed Tuberculosis Paradoxical Reaction Associated with Tumor Necrosis Factor Inhibitors
American Journal of Respiratory and Critical Care Medicine·2024· 3 cited
Cortisol on the Clock: Systemic Circadian Disruption in Severe Alpha-1 Antitrypsin Deficiency
2024
Long-term Follow-up of Pi[asterisk]ZZ Alpha-1 Antitrypsin Deficient Patients Receiving Intravenous Alpha-1 Antitrypsin Augmentation Therapy
2024
Family Screening in ZZ Alpha-1 Antitrypsin Deficiency - Exposing the Hidden Burden of Liver Disease
2024
Null Gives a Lot: A Rare Heterozygotic Alpha-1 Antitrypsin Deficiency Mutation In Ireland, Z Null Porto; A Case Report
2024
Examining the approach to medical remediation programmes—an observational study
Irish Journal of Medical Science (1971 -)·2024Open Access
Reply to Chan: Identification of Alpha-1 Antitrypsin–Deficient Subjects with Normal Spirometry Who May Benefit from Alpha-1 Antitrypsin Replacement
American Journal of Respiratory and Critical Care Medicine·2024Open Access
Alpha-1 Antitrypsin Augmentation and the Liver Phenotype of Adults With Alpha-1 Antitrypsin Deficiency (Genotype Pi∗ZZ)
Clinical Gastroenterology and Hepatology·2023· 11 citedOpen Access
Long-term follow-up of Pi*ZZ alpha-1 antitrypsin deficient patients receiving intravenous alpha-1 antitrypsin augmentation therapy
2023· 1 cited
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Frequent Co-authors

Noel G. McElvaney(36), Tomás P. Carroll(23), R.C. Heeney(20), Cedric Gunaratnam(18), Oisín F. McElvaney(16), M.P. Murphy(15), M. Herron(15), T.P. Carroll(14), L. Alhaddah(13), Oliver J. McElvaney(12), E. Leacy(12), Mark P. Murphy(10), Malcolm Herron(7), Suzanne Roche(7), Michelle Casey(7), S.M. Roche(7), N.G. Mc Elvaney(6), Emma Leacy(6), Natalie McEvoy(5), Georg‐Christian Funk(4)