David Schaffert

Aarhus University — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index2.3kcitations32works0.02yr avg
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Research Topics

RNA Interference and Gene Delivery(24), Advanced biosensing and bioanalysis techniques(21), DNA and Nucleic Acid Chemistry(9), Virus-based gene therapy research(8), Bacteriophages and microbial interactions(3)

Publications32 total

Central Application of Aliskiren, a Renin Inhibitor, Improves Outcome After Experimental Stroke Independent of Its Blood Pressure Lowering Effect
Frontiers in Neurology·2019· 10 citedOpen Access
Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids
Methods in molecular biology·2019· 8 cited
An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications
Molecular Therapy — Nucleic Acids·2017· 29 citedOpen Access
Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin‐Receptor Internalization Pathway
Small·2016· 139 cited
Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins
Nature Chemistry·2014· 175 citedOpen Access
Quantification of cellular uptake of DNA nanostructures by qPCR
Methods·2014· 65 cited
Towards Defined DNA and RNA Delivery Vehicles Using Nucleic Acid Nanotechnology
RNA technologies·2014· 1 cited
Synthesis of click‐reactive HPMA copolymers using RAFT polymerization for drug delivery applications
Journal of Polymer Science Part A Polymer Chemistry·2013· 35 citedOpen Access
Enzymatic Ligation of Large Biomolecules to DNA
ACS Nano·2013· 46 cited
Nucleic Acid Carrier Systems Based on Polyethylenimine Conjugates for the Treatment of Metastatic Tumors
Current Medicinal Chemistry·2013· 6 cited
Optimized siRNA-PEG Conjugates for Extended Blood Circulation and Reduced Urine Excretion in Mice
Theranostics·2013· 97 citedOpen Access
Construction of a 4 Zeptoliters Switchable 3D DNA Box Origami
ACS Nano·2012· 132 cited
Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids
Methods in molecular biology·2012· 18 cited
New Sequence-Defined Polyaminoamides with Tailored Endosomolytic Properties for Plasmid DNA Delivery
Bioconjugate Chemistry·2012· 49 citedOpen Access
Structure–activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides
Journal of Controlled Release·2012· 109 cited
Solid-phase-assisted synthesis of targeting peptide–PEG–oligo(ethane amino)amides for receptor-mediated gene delivery
Organic & Biomolecular Chemistry·2012· 70 citedOpen Access
siRNA Therapeutics: chances, Pitfalls and Future Potential
Therapeutic Delivery·2011· 1 cited
Festphasen‐basierte Synthese sequenzdefinierter T‐, i‐ und U‐Form‐Polymere für den pDNA‐ und siRNA‐Transfer
Angewandte Chemie·2011· 15 cited
Solid‐Phase Synthesis of Sequence‐Defined T‐, i‐, and U‐Shape Polymers for pDNA and siRNA Delivery
Angewandte Chemie International Edition·2011· 192 cited
pH‐Responsive Release of Acetal‐Linked Melittin from SBA‐15 Mesoporous Silica
Angewandte Chemie International Edition·2011· 73 cited
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Frequent Co-authors

Ernst Wagner(19), Manfred Ogris(11), Jørgen Kjems(7), Anders H. Okholm(6), Wolfgang Rödl(6), Christina Troiber(5), Christian Dohmen(5), Irene Martín(4), Naresh Badgujar(4), Thomas Fröhlich(3), Daniel Edinger(3), Raphaela Kläger(3), Philipp Hadwiger(3), Axel Schloßbauer(3), Thomas Bein(3), Anne Louise Bank Kodal(3), Jesper S. Nielsen(3), Kurt V. Gothelf(3), Rasmus Schøler Sørensen(3), Christine Spitzweg(3)