W. Clark Still

Columbia University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

65h-index29.5kcitations258works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(82), Synthetic Organic Chemistry Methods(32), Asymmetric Synthesis and Catalysis(27), Analytical Chemistry and Chromatography(25), Carbohydrate Chemistry and Synthesis(20)

Publications258 total

Application of the frozen atom approximation to the GB/SA continuum model for solvation free energy
Journal of Computational Chemistry·2001· 33 cited
Sequence-Selective Peptide Detection by Small Synthetic Chemosensors Selected from an Encoded Combinatorial Chemosensor Library
Bioorganic & Medicinal Chemistry Letters·2001· 13 cited
Combinatorial approach to the development of fluorescent sensors for nanomolar aqueous copper
Tetrahedron Letters·2000· 68 cited
A Synthetic Receptor Motif Designed for Extended Peptide Conformations
Tetrahedron·2000· 13 cited
ChemInform Abstract: Construction of Sequence‐Selective Peptide Receptors from Conformationally Restricted Eta‐ and Theta‐Amino Acids.
ChemInform·1999
Inhibition of gene expression in human cells through small molecule-RNA interactions
Proceedings of the National Academy of Sciences·1999· 64 citedOpen Access
Approximate solvent-accessible surface areas from tetrahedrally directed neighbor densities
Biopolymers·1999· 73 cited
Construction of sequence-selective peptide receptors from conformationally restricted eta- and theta- amino acids
Bioorganic & Medicinal Chemistry Letters·1999· 6 citedOpen Access
Highly sequence selective nonmacrocyclic two-armed receptors for peptides
Bioorganic & Medicinal Chemistry Letters·1999· 5 cited
Optimization of Gaussian surface calculations and extension to solvent-accessible surface areas
Journal of Computational Chemistry·1999· 75 cited
Fast, approximate algorithm for detection of solvent-inaccessible atoms
Journal of Computational Chemistry·1999· 41 cited
A new generation of fluorescent chemosensors demonstrate improved analyte detection sensitivity and photobleaching resistance
Bioorganic & Medicinal Chemistry Letters·1999· 28 citedOpen Access
Approximate atomic surfaces from linear combinations of pairwise overlaps (LCPO)
Journal of Computational Chemistry·1999· 1.2k cited
MC(JBW): Simple but smart Monte Carlo algorithm for free energy simulations of multiconformational molecules
Journal of Computational Chemistry·1998· 14 cited
Enantioselective Resolving Resins from a Combinatorial Library. Kinetic Resolution of Cyclic Amino Acid Derivatives
Journal of the American Chemical Society·1998· 55 cited
Tweezers with Different Bite: Increasing the Affinity of Synthetic Receptors by Varying the Hinge Part
Angewandte Chemie International Edition·1998· 39 cited
Sampling potential energy surface of glycyl glycine peptide: Comparison of Metropolis Monte Carlo and stochastic dynamics
Journal of Computational Chemistry·1998· 3 cited
Neighbor-list reduction: Optimization for computation of molecular van der Waals and solvent-accessible surface areas
Journal of Computational Chemistry·1998· 42 cited
Neighbor-list reduction: Optimization for computation of molecular van der Waals and solvent-accessible surface areas
Journal of Computational Chemistry·1998· 5 cited
Molekulare Pinzetten mit unterschiedlichem Biß – Erhöhung der Affinität synthetischer Rezeptoren durch Variation der Gelenkgruppe
Angewandte Chemie·1998· 12 cited
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Frequent Co-authors

Thomas F. Hendrickson(4), Wayne C. Guida(3), George Chang(3), F. MOHAMADI(2), Mark A. Lipton(2), Anna Tempczyk(2), Peter S. Shenkin(2), John H. McDonald(2), David B. Collum(2), Daniel Kahne(2), C. Sreekumar(2), H. Peter Nestler(2), Toshiro Suenaga(2), T. L. MACDONALD(2), Frank Guarnieri(2), Allen Borchardt(2), Hanoch Senderowitz(2), Michaël Kahn(1), Abhijit Mitra(1), Nigel G. J. Richards(1)