Deeptak Verma

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Medicine · Health Sciences

19h-index1.9kcitations50works3.62yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(10), Protein Structure and Dynamics(9), Biochemical and Molecular Research(9), Enzyme Structure and Function(8), Enzyme Catalysis and Immobilization(7)

Publications50 total

Ketoreductase Engineering for a Chemoenzymatic Fluorination and Dynamic Kinetic Reduction Cascade
ACS Catalysis·2025· 4 cited
Profiling of Diverse Pyridoxal-5′-Phosphate Dependent Enzymes Reveals Promiscuous Aldolase Activity with (2-Azaaryl)methanamines
Journal of the American Chemical Society·2025· 1 citedOpen Access
Profiling of Diverse Pyridoxal-5’-Phosphate Dependent Enzymes Reveals Promiscuous Aldolase Activity with (2-Azaaryl)methanamines
2025Open Access
Modern Electro-Organic Approaches in Pharmaceutical Chemistry: Toward a Greener Future for APIs
International Journal of Pharmaceutical Research and Applications·2025Open Access
Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
Organic Process Research & Development·2024· 13 cited
Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
2023· 4 citedOpen Access
Amination of a Green Solvent via Immobilized Biocatalysis for the Synthesis of Nemtabrutinib
ACS Catalysis·2023· 25 citedOpen Access
Directed Evolution to Reverse Epoxide Hydrolase Enantioselectivity for <i>meso</i>‐3,4‐Epoxytetrahydrofuran
ChemCatChem·2023· 6 cited
Amination of a Green Solvent via Immobilized Biocatalysis for the Synthesis of Nemtabrutinib
2023· 1 citedOpen Access
Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening
ACS Synthetic Biology·2023· 2 citedOpen Access
Using enzymes to tame nitrogen-centred radicals for enantioselective hydroamination
Nature Chemistry·2022· 122 citedOpen Access
Successive remodeling of IgG glycans using a solid-phase enzymatic platform
Communications Biology·2022· 14 citedOpen Access
Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454
Journal of the American Chemical Society·2022· 45 cited
A kinase-cGAS cascade to synthesize a therapeutic STING activator
Nature·2022· 125 cited
Similarity based enzymatic retrosynthesis
Chemical Science·2022· 28 citedOpen Access
Using Enzymes to Tame Nitrogen-Centered Radicals for Enantioselective Hydroamination
2021· 2 citedOpen Access
Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19
ACS Central Science·2021· 181 citedOpen Access
Successive remodeling of IgG glycans using a solid-phase enzymatic platform
2021· 3 citedOpen Access
Building blocks and blueprints for bacterial autolysins
PLoS Computational Biology·2021· 26 citedOpen Access
Evolving to an Ideal Synthesis of Molnupiravir, an Investigational Treatment for COVID-19
2020· 6 citedOpen Access
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Frequent Co-authors

Dennis R. Livesay(13), Donald J. Jacobs(12), Chris Bailey‐Kellogg(10), Jacob H. Forstater(8), Kevin M. Maloney(8), Grant S. Murphy(8), Jeffrey C. Moore(6), Karl E. Griswold(6), Anna Fryszkowska(5), Oscar Alvizo(5), Margie Borra‐Garske(5), Da Duan(5), Shane T. Grosser(5), John A. McIntosh(5), Weilan Pan(5), Hsing‐I Ho(5), Patrick S. Fier(5), Paul N. Devine(4), Benjamin F. Mann(4), Nicholas Marshall(4)