Jennifer Venhorst

Netherlands Organisation for Applied Scientific Research — Netherlands

Computer Science · Physical Sciences

19h-index1.0kcitations40works2.52yr avg
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Research Topics

Computational Drug Discovery Methods(14), Pharmacogenetics and Drug Metabolism(8), Analytical Chemistry and Chromatography(5), Receptor Mechanisms and Signaling(5), Neurotransmitter Receptor Influence on Behavior(4)

Publications40 total

Improved Translational Relevance of In Vitro Fibrosis Models by Integrating IOX2-Mediated Hypoxia-Mimicking Pathways
Biomedicines·2025Open Access
Drug target assessments: classifying target modulation and associated health effects using multi-level BERT-based classification models
Bioinformatics Advances·2024· 2 citedOpen Access
Identifying patient subgroups in MASLD and MASH-associated fibrosis: molecular profiles and implications for drug development
Scientific Reports·2024· 4 citedOpen Access
Integrating text mining with network models for successful target identification: in vitro validation in MASH-induced liver fibrosis
Frontiers in Pharmacology·2024· 4 citedOpen Access
Oncostatin M: Risks and Benefits of a Novel Therapeutic Target for Atherosclerosis
Current Drug Targets·2022· 5 cited
Battling Enteropathogenic Clostridia: Phage Therapy for Clostridioides difficile and Clostridium perfringens
Frontiers in Microbiology·2022· 38 citedOpen Access
Predicting the Safety of Drug Targets
2019· 4 cited
Targettri: A toxicity-based triaging system for novel drug targets
Journal of Pharmacological and Toxicological Methods·2018
Analysis of HSP90 using a toxicity-based triaging approach for drug targets
Toxicology Letters·2017
Development of an intelligence platform for efficient drug Target Safety Assessments
Toxicology Letters·2016
A holistic approach to the safety assessment of exploratory drug targets
Journal of Pharmacological and Toxicological Methods·2016
The selective 5-HT 6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment
Neurobiology of Learning and Memory·2016· 22 cited
Optimization of N′-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket
Bioorganic & Medicinal Chemistry Letters·2016· 3 citedOpen Access
A holistic approach to the safety assessment of exploratory drug targets
Toxicology Letters·2015
Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: Alternative approaches
Regulatory Toxicology and Pharmacology·2015· 29 cited
Generation of Bayesian prediction models for OATP-mediated drug–drug interactions based on inhibition screen of OATP1B1, OATP1B1∗15 and OATP1B3
European Journal of Pharmaceutical Sciences·2015· 20 cited
WITHDRAWN: Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: An alternative approach
Regulatory Toxicology and Pharmacology·2014
In vitro data combined with human disease data to improve toxicological hazard assessment: the ASAT Knowledge Base
Data Archiving and Networked Services (DANS)·2014
A novel highly selective 5-HT6 receptor antagonist attenuates ethanol and nicotine seeking but does not affect inhibitory response control in Wistar rats
Behavioural Brain Research·2012· 37 cited
CCDC 817440: Experimental Crystal Structure Determination
The Cambridge Structural Database·2012Open Access
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Frequent Co-authors

Chris G. Kruse(11), Nico Vermeulen(10), Jan N. M. Commandeur(8), Natasja de Bruin(7), Arnold van Loevezijn(6), Lars Verschuren(6), Tanja Rouhani Rankouhi(5), Gino Kalkman(5), Eugene P. van Someren(5), F.J. van de Brug(5), Simon Folkertsma(5), Martina A.W. van der Neut(4), John H.N. Meerman(4), Cyrille Krul(4), Sara Núñez(3), Antonius ter Laak(3), Rob Onderwater(3), Wouter Bakker(3), Wouter de Looff(3), Stefan Verhoog(3)