Brianna N. Smith

Vanderbilt University Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index151citations48works0.72yr avg
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Research Topics

Protein Degradation and Inhibitors(27), Acute Myeloid Leukemia Research(18), Histone Deacetylase Inhibitors Research(17), Cancer-related gene regulation(17), Advanced biosensing and bioanalysis techniques(5)

Publications48 total

EWSR1 Fusion Driven Pediatric B-Acute Lymphoblastic Leukemia: Diagnosis and Review of Literature
Pediatric and Developmental Pathology·2026Open Access
474 Disabling PSGL-1 abrogates immune suppression and resistance to PD-1 blockade in pancreatic cancer
Regular and Young Investigator Award Abstracts·2025Open Access
420 Immune checkpoint blockade of PSGL-1 overcomes resistance to anti-PD-1 treatment in melanoma by enhancing effector T cell differentiation
Regular and Young Investigator Award Abstracts·2025Open Access
Deregulation and Shattering of Chromosomal Segments Containing Multiple Oncogenic Targets in the Pathogenesis of Diffuse Large B Cell Lymphoma, Not Otherwise Specified (DLBCL, NOS)
DNA·2024Open Access
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies
Proceedings of the National Academy of Sciences·2024· 10 citedOpen Access
Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
eLife·2024Open Access
Author response: Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Author response: Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Reviewer #2 (Public Review): Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024· 1 citedOpen Access
Reviewer #1 (Public Review): Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Figure S4 from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Figure S3 from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Table S2 from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Figure S2 from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Table S2 from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Data from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Data from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Table S1 from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
Figure S4 from Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia
2024Open Access
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Frequent Co-authors

Michael R. Savona(41), Maria P. Arrate(25), Haley E. Ramsey(21), Agnieszka E. Gorska(20), Alexander J. Silver(19), Andrew J. Monteith(18), Donovan Brown(18), Londa Fuller(18), Dalton Greenwood(17), Ashley D. Wise(17), Juan Liu(17), Sarah D. Olmstead(17), Jackson Watke(17), Jason W. Locasale(17), Matthew C. Stubbs(17), Jeffrey C. Rathmell(17), Gregory C. Howard(12), Shelly L. Lorey(12), Brian C. Grieb(12), Taekyu Lee(12)