Taekyu Lee

Vanderbilt University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index2.3kcitations76works3.12yr avg
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Research Topics

Protein Degradation and Inhibitors(15), Cell death mechanisms and regulation(8), Cancer-related gene regulation(8), Chronic Myeloid Leukemia Treatments(7), Synthesis and Characterization of Heterocyclic Compounds(7)

Publications76 total

Discovery of Macrocyclic Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors that Demonstrate Potent Cellular Efficacy and In Vivo Activity in a Mouse Solid Tumor Xenograft Model
Journal of Medicinal Chemistry·2025Open Access
Influence of NaCl on Phase Development and Corrosion Resistance of Portland Cement
Crystals·2025· 1 citedOpen Access
Effect of Heat Treatment Duration on the Recrystallization and Electrochemical Properties of Cold-Rolled Cantor-Type High-Entropy Alloy
Materials·2025Open Access
The Effect of Sulfur Concentration on the Crystallization and Electrochemical Behavior of Portland Cement
Crystals·2025· 1 citedOpen Access
Development of a radiation-shielded cryostat for the 28 GHz superconducting electron cyclotron resonance ion source
Journal of the Korean Physical Society·2025
Culture-based characterization of gut microbiota in inflammatory bowel disease
Frontiers in Microbiology·2025· 3 citedOpen Access
The Effect of Carbon on the Crystallization and Electrochemical Behavior of Portland Cement
Crystals·2025· 2 citedOpen Access
Impact of Ag Coating Thickness on the Electrochemical Behavior of Super Duplex Stainless Steel SAF2507 for Enhanced Li-Ion Battery Cases
Crystals·2025· 3 citedOpen Access
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies
Proceedings of the National Academy of Sciences·2024· 10 citedOpen Access
Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent <i>In Vivo</i> Activities in Mouse Models of Hematological and Solid Tumors
Journal of Medicinal Chemistry·2024· 14 citedOpen Access
Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PL<sup>pro</sup>)
ACS Medicinal Chemistry Letters·2024· 12 citedOpen Access
Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
eLife·2024Open Access
Author response: Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Medical Ethics and Artificial Intelligence in Neurosurgery—How Should We Prepare?
World Neurosurgery·2024· 9 cited
Author response: Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Reviewer #2 (Public Review): Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024· 1 citedOpen Access
Reviewer #1 (Public Review): Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
2024Open Access
Robotic surgery for microvascular decompression in hemifacial spasm: a feasibility study
Neurofunction·2024· 5 citedOpen Access
A Study on the Improvement of the Superconducting Magnet System for the 28 GHz SC-ECRIS at KBSI
IEEE Transactions on Applied Superconductivity·2024· 1 cited
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Frequent Co-authors

Stephen W. Fesik(31), Edward T. Olejniczak(15), John Sensintaffar(14), Bin Zhao(13), William P. Tansey(12), Michael R. Savona(11), Brian C. Grieb(9), Shelly L. Lorey(9), Gregory C. Howard(9), James C. Tarr(8), Allison L. Arnold(8), William Moore(8), Soumita Goswami(8), Brianna N. Smith(8), Subrata Shaw(7), Olivia W. Rossanese(7), Purvi Patel(7), Tina Tsui(7), Andrea C. Florian(7), Macey J. Slota(7)