Rajarshi Choudhury

GlaxoSmithKline (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index736citations32works0.32yr avg
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Research Topics

RNA and protein synthesis mechanisms(6), RNA Research and Splicing(6), Ubiquitin and proteasome pathways(6), Genomics and Chromatin Dynamics(4), Epigenetics and DNA Methylation(4)

Publications32 total

Abstract 1676: POLB as a novel synergistic target for combination therapy with niraparib
Cancer Research·2025
Set2 methyltransferase facilitates cell cycle progression by maintaining transcriptional fidelity
UNC Libraries·2024· 1 citedOpen Access
APC/C and SCFcyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry
Cell Reports·2024Open Access
Abstract 6175: CDK8 inhibition potentiates the efficacy of niraparib in homologous recombination proficient cancer cell lines
Cancer Research·2023
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
PLoS Biology·2020· 19 citedOpen Access
In vivo analysis of trypanosome mitochondrial RNA function by artificial site-specific RNA endonuclease-mediated knockdown
UNC Libraries·2020Open Access
Treatment of Type 1 Myotonic Dystrophy by Engineering Site-specific RNA Endonucleases that Target (CUG) n Repeats
UNC Libraries·2020· 1 citedOpen Access
Engineering RNA endonucleases with customized sequence specificities
UNC Libraries·2020Open Access
A complex network of factors with overlapping affinities represses splicing through intronic elements
UNC Libraries·2020· 5 citedOpen Access
The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration
UNC Libraries·2020Open Access
VprBP/DCAF1 Regulates the Degradation and Nonproteolytic Activation of the Cell Cycle Transcription Factor FoxM1
UNC Libraries·2020· 1 citedOpen Access
APC/C and SCF cyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry
UNC Libraries·2020Open Access
The E3 Ubiquitin Ligase SCF(Cyclin F) Transmits AKT Signaling to the Cell-Cycle Machinery
UNC Libraries·2020Open Access
<i>In silico</i> APC/C substrate discovery reveals cell cycle degradation of chromatin regulators including UHRF1
2020· 1 citedOpen Access
Set2 methyltransferase facilitates cell cycle progression by maintaining transcriptional fidelity
Nucleic Acids Research·2017· 26 citedOpen Access
The E3 Ubiquitin Ligase SCF(Cyclin F) Transmits AKT Signaling to the Cell-Cycle Machinery
Cell Reports·2017· 54 citedOpen Access
The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome
Journal of Biological Chemistry·2017· 73 citedOpen Access
VprBP/DCAF1 Regulates the Degradation and Nonproteolytic Activation of the Cell Cycle Transcription Factor FoxM1
Molecular and Cellular Biology·2017· 44 citedOpen Access
Abstract A03: SCFCyclin F connects AKT signaling to the core cell cycle oscillator
Molecular Cancer Research·2016
APC/C and SCF cyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry
Cell Reports·2016· 82 citedOpen Access
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Frequent Co-authors

Michael J. Emanuele(13), Zefeng Wang(11), Jennifer L. Kernan(9), Christine A. Mills(8), Thomas Bonacci(7), Anthony Arceci(7), Xianxi Wang(6), Narayan S. Punekar(6), Yang Wang(5), Yi‐Hsuan Tsai(4), Daniel J. Burke(4), Daniel Domínguez(3), Timothy B. Branigan(3), James A. DeCaprio(3), Michael B. Major(3), Xinshu Xiao(2), Jianming Zhang(2), Alex Robertson(2), Meng Ma(2), Christopher B. Burge(2)