Tereza Smejkalová

Czech Academy of Sciences — Czech Republic

Neuroscience · Life Sciences

15h-index1.3kcitations34works5.52yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(25), Receptor Mechanisms and Signaling(12), Ion channel regulation and function(8), Genetics and Neurodevelopmental Disorders(7), Lipid Membrane Structure and Behavior(4)

Publications34 total

Mice carrying a GluN2B protein-truncating variant have altered NMDA receptor subunit composition and their behavior recapitulates patient phenotypes
Cellular and Molecular Life Sciences·2026Open Access
Phenotype of mice carrying an NMDA receptor GluN2B protein-truncating variant associated with intellectual disability
2025Open Access
Disruption of <i>grin2A</i> , an Epilepsy-Associated Gene, Produces Altered Spontaneous Swim Behavior in Zebrafish
Journal of Neuroscience·2025· 1 citedOpen Access
Disruption of <i>grin2A</i> , an epilepsy-associated gene, produces altered spontaneous swim behavior in zebrafish
2025Open Access
Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology
Physiological Research·2024· 25 citedOpen Access
Characterization of Mice Carrying a Neurodevelopmental Disease-Associated GluN2B(L825V) Variant
Journal of Neuroscience·2024· 12 citedOpen Access
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids
Cellular and Molecular Life Sciences·2024· 3 citedOpen Access
Analysis of Surface Expression of NMDAR Subunits in Primary Hippocampal Neurons
Methods in molecular biology·2024· 3 cited
Effects of Pregnanolone Glutamate and Its Metabolites on GABA<sub>A</sub> and NMDA Receptors and Zebrafish Behavior
ACS Chemical Neuroscience·2023· 10 citedOpen Access
Pregnane‐based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss‐of‐function disease‐associated <i>GRIN</i> mutations
British Journal of Pharmacology·2022· 13 citedOpen Access
Pharmacokinetic, pharmacodynamic, and behavioural studies of deschloroketamine in Wistar rats
British Journal of Pharmacology·2021· 11 citedOpen Access
Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms
British Journal of Pharmacology·2021· 11 citedOpen Access
Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity
Journal of Neuroscience·2021· 22 citedOpen Access
Energy Dispersive X-Ray Spectroscopy Of Doped PVDF Fibers
2021Open Access
Cholesterol modulates presynaptic and postsynaptic properties of excitatory synaptic transmission
Scientific Reports·2020· 76 citedOpen Access
Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor
Journal of Neuroscience·2020· 28 citedOpen Access
Surface Functionalization of Nanocrystalline and Nanostructured Diamond to Form Interface with Newborn and Adult Neurons
The FASEB Journal·2019
Molecular Functionalization of Planar Nanocrystalline and Porous Nanostructured Diamond to Form an Interface with Newborn and Adult Neurons
physica status solidi (b)·2018· 11 citedOpen Access
Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif
Frontiers in Pharmacology·2018· 11 citedOpen Access
7-METHOXYDERIVATIVE OF TACRINE IS A ‘FOOT-IN-THEDOOR’ BLOCKER OF GluN1/GluN2 AND GluN1/GluN3 NMDA RECEPTORS
MMSL·2018
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Frequent Co-authors

Ladislav Vyklický(23), Miloslav Kořı́nek(20), Barbora Hrčka Krausová(20), Jiří Černý(15), Aleš Balík(14), Vojtěch Vyklický(11), Martin Hořák(11), Bohdan Kysilov(11), Hana Chodounská(11), Jan Krůšek(10), Eva Kudová(10), Klevinda Fili(8), Mark Dobrovolski(7), Vera Abramova(7), Paulína Božíková(7), Martina Kaniaková(5), Katarína Lichnerová(5), Catherine S. Woolley(5), Marek Ladislav(5), Eni Tomović(5)