Karen Castillo

Valparaiso University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index4.5kcitations61works7.02yr avg
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Research Topics

Ion channel regulation and function(19), Cardiac electrophysiology and arrhythmias(12), Autophagy in Disease and Therapy(11), Neuroscience and Neuropharmacology Research(6), Endoplasmic Reticulum Stress and Disease(6)

Publications59 total

Papilledema in a Patient on Hemodialysis
Journal of the American Society of Nephrology·2025
Computer Assisted Analysis of Acrosomal Status in Sperm Cells Using Inverted Fluorescence Microscopy and Computational Intelligence for Biotechnology Applications
2025
The bisphosphonate zoledronic acid produces analgesia by inhibiting the transient receptor potential vanilloid 1 (TRPV1) channel.
2025Open Access
Effects of Electronic Cigarettes on Airway Epithelium: A Novel Exposure System and In-Vitro Model
2024
Large conductance voltage-and calcium-activated K+ (BK) channel in health and disease
Frontiers in Pharmacology·2024· 29 citedOpen Access
A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel
Frontiers in Pharmacology·2024· 13 citedOpen Access
ROLE OF GLYCINE RECEPTORS IN THE NEUROIMMUNE MODULATION OF THE CHRONIC PAIN
IBRO Neuroscience Reports·2023· 1 citedOpen Access
The bisphosphonate zoledronic acid is a TRPV1 channel inhibitor
Biophysical Journal·2023· 2 citedOpen Access
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects
Frontiers in Pharmacology·2022· 31 citedOpen Access
Correction: Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress
PLoS ONE·2022Open Access
Correction: Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress
SHILAP Revista de lepidopterología·2022Open Access
Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1
Science Advances·2021· 28 citedOpen Access
BAX inhibitor‐1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response
The EMBO Journal·2021· 1 citedOpen Access
Sex Differences In Central Inflammatory Pain Sensitization Are Associated With Differential Expression Of Glycine Receptors And Glp-1 At The Spinal Cord
Journal of Neurological Sciences and Research.·2021Open Access
Effects of Interleukin-1β in Glycinergic Transmission at the Central Amygdala
Frontiers in Pharmacology·2021· 8 citedOpen Access
Temperature Sensitivity in the TRPM8 Channel is Harbored at the C-Terminal Domain
Biophysical Journal·2021Open Access
Arachidonic acid effect on the allosteric gating mechanism of BK (Slo1) channels associated with the β1 subunit
Biochimica et Biophysica Acta (BBA) - Biomembranes·2021· 11 citedOpen Access
A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels
Proceedings of the National Academy of Sciences·2020· 33 citedOpen Access
TRPV1-Estradiol Stereospecific Relationship Underlies Cell Survival in Oxidative Cell Death
Frontiers in Physiology·2020· 18 citedOpen Access
Sex differences in central inflammatory pain sensitization are associated with differential expression of glycine receptors and GLP-1 at the spinal cord
2020· 1 citedOpen Access
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Frequent Co-authors

Ramón Latorre(20), Claudio Hetz(13), Carlos González(11), Melissa Nassif(8), Osvaldo Álvarez(7), Amaury Pupo(7), Willy Carrasquel-Ursulaez(6), Fernando D. González‐Nilo(6), Yenisleidy Lorenzo(6), Felipe A. Court(5), David Báez-Nieto(5), Gustavo F. Contreras(4), Alan Neely(4), Ignacio Díaz-Franulic(4), Diego Rojas‐Rivera(4), Fernanda Lisbona(4), Álvaro Glavic(4), Juan Bacigalupo(4), Benjamı́n Caballero(3), Sebastian Schuck(3)