Osvaldo Álvarez

Charles University — Czech Republic

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index4.5kcitations96works0.02yr avg
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Research Topics

Ion channel regulation and function(52), Cardiac electrophysiology and arrhythmias(28), Neuroscience and Neuropharmacology Research(16), Neuroscience and Neural Engineering(16), Lipid Membrane Structure and Behavior(15)

Publications96 total

Low-Temperature Collisions of O<sup>–</sup> Anions with CH<sub>4</sub> and C<sub>2</sub>H<sub>2</sub>: Reaction Rate Coefficients and Product Branching Fractions
The Journal of Physical Chemistry A·2025
BPS2025 - Gating and ionic currents reveal how the LRRC26 (γ1) subunit modulates the BK channel gating
Biophysical Journal·2025
HIGHLY SPECIFIC NON-VIRAL GENE EDITING WITH P-KLKB1-101 FOR HEREDITARY ANGIOEDEMA
Annals of Allergy Asthma & Immunology·2024
Trapping Charge Mechanism in Hv1 Channels (CiHv1)
International Journal of Molecular Sciences·2023· 7 citedOpen Access
Mechanism of voltage sensing in Ca <sup>2+</sup> - and voltage-activated K <sup>+</sup> (BK) channels
Proceedings of the National Academy of Sciences·2022· 22 citedOpen Access
Expression of H<sub>v</sub>1 proton channels in myeloid-derived suppressor cells (MDSC) and its potential role in T cell regulation
Proceedings of the National Academy of Sciences·2022· 16 citedOpen Access
Molecular mechanism for stabilization of voltage sensor active state in proton channel (CiHv1)
Biophysical Journal·2022
Hv1 channel is a key target in immunosuppression in myeloid-derived suppressor cells (MDSC)
Biophysical Journal·2022
The voltage sensor is responsible for ΔpH dependence in H <sub>v</sub> 1 channels
Proceedings of the National Academy of Sciences·2021· 30 citedOpen Access
The pH Modulation of the Voltage Sensor in the Voltage-Gated Proton Channel (HV1)
Biophysical Journal·2021Open Access
Calcium-driven regulation of voltage-sensing domains in BK channels
eLife·2019· 25 citedOpen Access
Author response: Calcium-driven regulation of voltage-sensing domains in BK channels
2019· 1 citedOpen Access
pH Dependence of a Monomeric Non-Conducting Voltage-Gated Proton Channel (HV1)
Biophysical Journal·2019
Calcium-driven regulation of voltage-sensing domains in BK channels
2019· 4 citedOpen Access
Methods for Investigating TRP Channel Gating
Methods in molecular biology·2019· 2 cited
Hipotiroidismo refractario idiopático: un caso clínico
2019
Gating charge displacement in a monomeric voltage-gated proton (H <sub>v</sub> 1) channel
Proceedings of the National Academy of Sciences·2018· 37 citedOpen Access
Determination of the Stoichiometry between α- and γ1 Subunits of the BK Channel Using LRET
Biophysical Journal·2018· 17 citedOpen Access
The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels
The Journal of General Physiology·2018· 31 citedOpen Access
Properties of the Voltage-Gated Proton Channel Gating Currents
Biophysical Journal·2018· 2 citedOpen Access
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Frequent Co-authors

Ramón Latorre(32), Carlos González(13), Willy Carrasquel-Ursulaez(4), Alan Neely(4), Ximena Cecchi(4), George Eisenman(4), Andrés F. Oberhauser(3), Karen Castillo(3), Fernando D. González‐Nilo(3), Gustavo F. Contreras(3), Juan P. Castillo(3), Cecilia Vergara(3), Pedro Labarca(2), Edward Moczydlowski(2), Alfredo Villarroel(2), Enrico Stefani(2), Daniel Wolff(2), María Isabel Behrens(2), Eduardo Rosenman(2), Francisco Bezanilla(2)