Kelsey L. Swingle

California University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.3kcitations31works27.62yr avg
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Research Topics

RNA Interference and Gene Delivery(21), Advanced biosensing and bioanalysis techniques(10), Virus-based gene therapy research(7), Nanoparticle-Based Drug Delivery(3), Pregnancy and preeclampsia studies(3)

Publications31 total

Drug-loaded bispecific T cell nanoengager overcomes T cell exhaustion for potent cancer immunotherapy
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Circular RNA lipid nanoparticle vaccine against SARS-CoV-2
Proceedings of the National Academy of Sciences·2025· 4 citedOpen Access
Engineering Nanoparticles for Gynecologic Cancer Therapy
ACS Nano·2025· 5 cited
High-throughput <i>in vivo</i> screening using barcoded mRNA identifies lipid nanoparticles with extrahepatic tropism for cancer immunotherapy
2025· 1 citedOpen Access
Probing the Role of Lipid Nanoparticle Elasticity on mRNA Delivery to the Placenta
Nano Letters·2025· 7 cited
Publisher Correction: Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia
Nature·2025· 3 citedOpen Access
In vitro development and in vivo evaluation of intra-articular GUSB mRNA therapy for mucopolysaccharidosis type VII
Molecular Genetics and Metabolism·2025
Peptide-Functionalized Lipid Nanoparticles for Targeted Systemic mRNA Delivery to the Brain
Nano Letters·2024· 84 cited
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia
Nature·2024· 79 citedOpen Access
Optimization of the activity and biodegradability of ionizable lipids for mRNA delivery via directed chemical evolution
Nature Biomedical Engineering·2024· 43 cited
Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery
Nature Nanotechnology·2024· 73 citedOpen Access
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells
Proceedings of the National Academy of Sciences·2024· 31 citedOpen Access
High-Throughput <i>In Vivo</i> Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route
ACS Nano·2024· 38 cited
Optimized microfluidic formulation and organic excipients for improved lipid nanoparticle mediated genome editing
Lab on a Chip·2024· 17 citedOpen Access
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism
Small·2023· 162 cited
mRNA Lipid Nanoparticles for <i>Ex Vivo</i> Engineering of Immunosuppressive T Cells for Autoimmunity Therapies
Nano Letters·2023· 36 cited
Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering
Advanced Healthcare Materials·2023· 83 citedOpen Access
Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta
Small·2023· 33 citedOpen Access
Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease
ACS Nano·2023· 60 citedOpen Access
Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles
PLoS Biology·2023· 51 citedOpen Access
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Frequent Co-authors

Michael J. Mitchell(30), Alex G. Hamilton(18), Drew Weissman(14), Mohamad‐Gabriel Alameh(13), Margaret M. Billingsley(11), Ajay S. Thatte(11), Hannah C. Safford(11), Rohan Palanki(11), Xuexiang Han(10), Ningqiang Gong(7), Hannah C. Geisler(7), Emily L. Han(7), Amanda M. Murray(7), Lulu Xue(6), Ryann A. Joseph(6), Alvin J. Mukalel(5), William H. Peranteau(5), Rakan El‐Mayta(4), Savan K. Patel(4), Kaitlin Mrksich(4)