Matthew C. J. Yip

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index741citations22works6.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(7), RNA modifications and cancer(7), Ubiquitin and proteasome pathways(6), Endoplasmic Reticulum Stress and Disease(4), RNA Research and Splicing(3)

Publications22 total

ZNFX1, an immunoregulatory RNA helicase and E3 ubiquitin ligase, assembles into pleiomorphic polymers
2025· 1 citedOpen Access
Structure of the TXNL1-bound proteasome
Nature Structural & Molecular Biology·2025· 3 citedOpen Access
Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma
Molecular Cell·2025· 9 citedOpen Access
Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma
2025· 2 citedOpen Access
Structure of the TXNL1-bound proteasome
2024· 3 citedOpen Access
Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213
EMBO Reports·2024· 11 citedOpen Access
Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213
2024· 2 cited
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center
Nature Chemical Biology·2024· 17 citedOpen Access
Mechanism of client selection by the protein quality-control factor UBE2O
Nature Structural & Molecular Biology·2022· 21 citedOpen Access
Cryo-EM structure of an active bacterial TIR–STING filament complex
Nature·2022· 114 citedOpen Access
Structural insights into metazoan pretargeting GET complexes
Nature Structural & Molecular Biology·2021· 14 citedOpen Access
Detecting and Rescuing Stalled Ribosomes
Trends in Biochemical Sciences·2021· 96 citedOpen Access
Ddi1 is a ubiquitin-dependent protease
Proceedings of the National Academy of Sciences·2020· 83 citedOpen Access
ELAC1 Repairs tRNAs Cleaved during Ribosome-Associated Quality Control
Cell Reports·2020· 44 citedOpen Access
Structure and activation mechanism of the BBSome membrane protein trafficking complex
eLife·2020· 88 citedOpen Access
Author response: Structure and activation mechanism of the BBSome membrane protein trafficking complex
2019Open Access
Structure of the bovine BBSome complex
2019
Structure of the bovine BBSome:ARL6:GTP complex
2019
Structure and activation mechanism of the BBSome membrane-protein trafficking complex
2019· 4 citedOpen Access
Mechanism for recycling tRNAs on stalled ribosomes
Nature Structural & Molecular Biology·2019· 76 cited
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Frequent Co-authors

Sichen Shao(13), Alan Brown(5), Miao Gui(5), Christopher Nardone(4), Jingjing Gao(4), Stephen J. Elledge(4), Xin Gu(4), Frederick H. Koh(4), Alexander F. A. Keszei(3), Sandeep Singh(3), Steven P. Gygi(3), Katerina Naydenova(3), Ceara Harper(3), Elsje G. Otten(3), Keith B. Boyle(3), Felix Randow(3), M.R. Baird(2), J. Murray(2), Ana Crespillo-Casado(2), Prathyush Pothukuchi(2)