David Jeruzalmi

The Graduate Center, CUNY — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index3.4kcitations74works2.22yr avg
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Research Topics

DNA Repair Mechanisms(30), Bacterial Genetics and Biotechnology(29), DNA and Nucleic Acid Chemistry(18), Enzyme Structure and Function(14), RNA and protein synthesis mechanisms(12)

Publications74 total

Distinct quaternary states, intermediates, and autoinhibition during loading of the DnaB-replicative helicase by the phage λP helicase loader
Nucleic Acids Research·2025Open Access
DnaB and DciA: mechanisms of helicase loading and translocation on ssDNA
Nucleic Acids Research·2025· 4 citedOpen Access
A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization
Molecular Cell·2025· 5 cited
Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair
Nature Communications·2025· 4 citedOpen Access
DnaB and DciA: Mechanisms of Helicase Loading and Translocation on ssDNA
2024Open Access
Mechanistic understanding of the Nucleotide Excision Repair: structural bases of damage detection process by UvrA and lesion hand-off to UvrB.
2024Open Access
How a disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization
2023· 3 citedOpen Access
Distinct Quaternary States, Intermediates, and Autoinhibition During Loading of the DnaB-Replicative Helicase by the Phage λP Helicase Loader
2022· 2 citedOpen Access
Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase
Science Advances·2022· 19 citedOpen Access
Decision letter: Cryo-EM structures reveal that RFC recognizes both the 3′- and 5′-DNA ends to load PCNA onto gaps for DNA repair
2022Open Access
Decision letter: A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA
2022Open Access
The partner-swapping sliding clamp loader exposed
Nature Structural & Molecular Biology·2022· 1 cited
Convergent evolution in two bacterial replicative helicase loaders
Trends in Biochemical Sciences·2022· 15 citedOpen Access
Structural Basis for the Calmodulin-Mediated Activation of eEF-2K
2022Open Access
A Peek Inside the Machines of Bacterial Nucleotide Excision Repair
International Journal of Molecular Sciences·2021· 28 citedOpen Access
Real-time investigation of the roles of ATP hydrolysis by UvrA and UvrB during DNA damage recognition in nucleotide excision repair
DNA repair·2020· 8 cited
Structural basis for initiation of transcription from an RNA polymerase-promoter complex
WORLD SCIENTIFIC eBooks·2020· 8 cited
Wss1 homolog from <i>Candida albicans</i> and its role in DNA–protein crosslink tolerance
Molecular Microbiology·2020· 8 citedOpen Access
Mechanisms of opening and closing of the bacterial replicative helicase
Acta Crystallographica Section A Foundations and Advances·2019Open Access
The ATPase mechanism of UvrA2 reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair
Nucleic Acids Research·2019· 17 citedOpen Access
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Frequent Co-authors

Danaya Pakotiprapha(11), John Kuriyan(9), Mike O’Donnell(8), Jillian Chase(6), Thomas A. Steitz(5), Martin A. Samuels(5), G.M.T. Cheetham(4), Alex J. Noble(4), Edward T. Eng(4), Amédée des Georges(4), Paul Dominic B. Olinares(4), Brian T. Chait(4), Yanxiang Zhao(3), Venkata P. Dandey(3), Hui Wei(3), Julia Brasch(3), Priyamvada Acharya(3), Yong Zi Tan(3), Zhening Zhang(3), Laura Y. Kim(3)