Martin Himmelbauer

Biogen (United States) — United States

Chemistry · Physical Sciences

11h-index309citations25works5.02yr avg
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Research Topics

Synthetic Organic Chemistry Methods(10), Marine Sponges and Natural Products(9), Microbial Natural Products and Biosynthesis(7), Crystallization and Solubility Studies(6), X-ray Diffraction in Crystallography(6)

Publications25 total

Novel Immuno-Immobilization Mass-Spectrometry-Based Assay to Enable Structure–Activity Relationship Development of Emopamil Binding Protein (EBP) Inhibitors
Journal of the American Society for Mass Spectrometry·2025
Macrocyclic Rearrangement Ion Fragmentation of Glutathione Conjugates of Cyclobutane-Containing Covalent BTK Inhibitors
Journal of the American Society for Mass Spectrometry·2025
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis
Journal of Medicinal Chemistry·2024· 15 citedOpen Access
Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation <i>In Vivo</i>
Journal of Medicinal Chemistry·2021· 14 citedOpen Access
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo
Journal of Medicinal Chemistry·2021· 32 citedOpen Access
Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors
ACS Medicinal Chemistry Letters·2020· 22 citedOpen Access
Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors
Journal of Medicinal Chemistry·2019· 34 citedOpen Access
CCDC 1922931: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
CCDC 1936661: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
CCDC 1936974: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
Biomimetic Synthesis of Meroterpenoids by Dearomatization‐Driven Polycyclization
Angewandte Chemie International Edition·2019· 41 citedOpen Access
Biomimetic Synthesis of Meroterpenoids by Dearomatization‐Driven Polycyclization
Angewandte Chemie·2019· 9 cited
An Approach Toward the Bridged 14‐Membered Carbon Macrocycle of Bielschowskysin
European Journal of Organic Chemistry·2016· 9 citedOpen Access
ChemInform Abstract: An Approach to the Carbon Backbone of Bielschowskysin. Part 1. Photocyclization Strategy.
ChemInform·2014
ChemInform Abstract: An Approach to the Carbon Backbone of Bielschowskysin. Part 2. Non‐Photochemical Strategy.
ChemInform·2014
An Approach to the Carbon Backbone of Bielschowskysin, Part 1: Photocyclization Strategy
European Journal of Organic Chemistry·2013· 18 cited
An Approach to the Carbon Backbone of Bielschowskysin, Part 2: Non‐Photochemical Strategy
European Journal of Organic Chemistry·2013· 13 cited
Photochemical and Thermal [2 + 2] Cycloaddition to Generate the Bicyclo[3.2.0]heptane Core of Bielschowskysin
European Journal of Organic Chemistry·2013· 23 cited
A Palladium-Catalyzed Carbo-oxygenation: The Bielschowskysin Case
Organic Letters·2013· 32 citedOpen Access
CCDC 943950: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
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Frequent Co-authors

Jean‐Baptiste Farcet(11), Johann Mulzer(10), Paramasivam Murugan(6), Zachary Powers(5), Adam Scharf(5), Andrea Cheng(5), Takaaki Mitsuhashi(5), Lena Barra(5), Yoshimasa Taniguchi(5), Makoto Fujita(5), Ikuro Abe(5), J. Howard Jones(5), Rab Gilfillan(5), Felix González-López de Turiso(5), Kristopher King(4), D.J. Marcotte(4), Joseph C. Santoro(4), Thomas Hesson(4), Julien Gagnepain(4), Zhili Xin(3)