Diane Ethier

TransCanada (Canada) — Canada

Medicine · Health Sciences

29h-index4.3kcitations56works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Inflammatory mediators and NSAID effects(21), Asthma and respiratory diseases(14), Estrogen and related hormone effects(11), Synthesis and biological activity(7), Protease and Inhibitor Mechanisms(5)

Publications56 total

Trisubstituted ureas as potent and selective mPGES-1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2011· 23 citedOpen Access
Corrigendum to “Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C” [Bioorg. Med. Chem. Lett. 19 (2009) 5392]
Bioorganic & Medicinal Chemistry Letters·2010· 2 cited
Corrigendum to “Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C” [Bioorg. Med. Chem. Lett. 19 (2009) 5392]
Bioorganic & Medicinal Chemistry Letters·2009
Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 61 citedOpen Access
Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C
Bioorganic & Medicinal Chemistry Letters·2009· 42 citedOpen Access
In Vivo Inhibition of Serine Protease Processing Requires a High Fractional Inhibition of Cathepsin C
Molecular Pharmacology·2008· 53 cited
Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2007· 128 citedOpen Access
Inhibition of the Activation of Multiple Serine Proteases with a Cathepsin C Inhibitor Requires Sustained Exposure to Prevent Pro-enzyme Processing
Journal of Biological Chemistry·2007· 77 citedOpen Access
Substituted coumarins as potent 5-lipoxygenase inhibitors
Bioorganic & Medicinal Chemistry Letters·2006· 49 citedOpen Access
Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: Structure–activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor
Bioorganic & Medicinal Chemistry Letters·2005· 30 citedOpen Access
An Automated Multistep High-Throughput Screening Assay for the Identification of Lead Inhibitors of the Inducible Enzyme mPGES-1
SLAS DISCOVERY·2005· 20 citedOpen Access
Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886
Bioorganic & Medicinal Chemistry Letters·2005· 142 citedOpen Access
5-Oxo-6,8,11,14-eicosatetraenoic Acid Stimulates the Release of the Eosinophil Survival Factor Granulocyte/Macrophage Colony-stimulating Factor from Monocytes
Journal of Biological Chemistry·2004· 34 citedOpen Access
Deletion of Microsomal Prostaglandin E2 (PGE2) Synthase-1 Reduces Inducible and Basal PGE2 Production and Alters the Gastric Prostanoid Profile
Journal of Biological Chemistry·2004· 118 citedOpen Access
Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors
Bioorganic & Medicinal Chemistry Letters·2003· 15 citedOpen Access
Etoricoxib (MK-0663): Preclinical Profile and Comparison with Other Agents That Selectively Inhibit Cyclooxygenase-2
Journal of Pharmacology and Experimental Therapeutics·2001· 456 citedOpen Access
Gunnar Myrdal and his works
University of Toronto eBooks·2001· 6 cited
Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors
Bioorganic & Medicinal Chemistry Letters·1999· 29 citedOpen Access
Substituted indoles as potent and orally active 5-lipoxygenase activating protein (FLAP) inhibitors
Bioorganic & Medicinal Chemistry Letters·1999· 14 citedOpen Access
Rofecoxib [Vioxx, MK-0966; 4-(4′-Methylsulfonylphenyl)-3-phenyl-2-(5 H)-furanone]: A Potent and Orally Active Cyclooxygenase-2 Inhibitor. Pharmacological and Biochemical Profiles
Journal of Pharmacology and Experimental Therapeutics·1999· 397 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Denis Riendeau(19), Jocelyne Guay(18), Christine Brideau(16), Yves Girard(16), S. Charleson(14), Joseph A. Mancini(14), Robert N. Young(11), Philip Tagari(11), M. David Percival(10), Chi‐Chung Chan(10), Nathalie Méthot(10), Richard W. Friesen(9), Robert J. Gordon(9), Robert Zamboni(9), Joel Rubin(9), Elizabeth Wong(8), Petpiboon Prasit(8), Jilly F. Evans(8), Wanda Cromlish(7), Stacia Kargman(7)