C. Smee

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index889citations50works0.02yr avg
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Research Topics

Metabolism and Genetic Disorders(9), Hippo pathway signaling and YAP/TAZ(7), Peroxisome Proliferator-Activated Receptors(5), Enzyme Structure and Function(5), Protein Kinase Regulation and GTPase Signaling(4)

Publications47 total

1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole
2018
Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
2018
Biological Evaluation of Benzothiazole Ethyl Urea Inhibitors of Bacterial Type II Topoisomerases
Antimicrobial Agents and Chemotherapy·2013· 34 citedOpen Access
Crystal structure of the human MGC45594 gene product in complex with diclofenac
2009
Corrigendum to “DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity” [Bioorg. Med. Chem. Lett. 19 (2009) 894]
Bioorganic & Medicinal Chemistry Letters·2009· 2 cited
DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity
Bioorganic & Medicinal Chemistry Letters·2008· 72 cited
Structure of Human Zinc-binding Alcohol Dehydrogenase 1 (ZADH1)
2008
High Throughput Production of Recombinant Human Proteins for Crystallography
Methods in molecular biology·2008· 100 cited
Baculovirus Expression Vector System: An Emerging Host for High-Throughput Eukaryotic Protein Expression
Methods in molecular biology·2008· 34 cited
Crystal structure of human UDP-glucose dehydrogenase product complex with UDP-glucuronate
2007
Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose
2007
Structure of the cytokine-like nuclear factor n-pac
2007· 1 cited
Crystal structure of human glycerol-3-phosphate dehydrogenase 1-like protein
2007
Crystal structure of human very long chain acyl-CoA dehydrogenase (ACADVL)
2007· 1 cited
Structure of human short-branched chain acyl-CoA dehydrogenase (ACADSB)
2007
The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
2007
Crystal structure of the Bromo domain 2 of human Bromodomain containing protein 3 (BRD3)
2007
Crystal structure of human calmodulin-dependent protein kinase I G
2006· 2 cited
Structure of aminoadipate-semialdehyde dehydrogenase
2006
Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
2006
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Frequent Co-authors

M. Sundström(38), C.H. Arrowsmith(37), F. von Delft(34), J. Weigelt(32), Udo Oppermann(22), G. Berridge(18), G. Bunkóczi(16), A.P. Turnbull(16), O. Gileadi(15), A.M. Edwards(15), E. Papagrigoriou(14), Jonathan M. Elkins(13), J.E. Debreczeni(12), K.L. Kavanagh(12), D. Doyle(12), P. Savitsky(11), C. Johansson(11), E. Ugochukwu(11), Neil Burgess(10), S. Colebrook(9)