Katie Leach

Australian Research Council — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index6.1kcitations89works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(45), Neuroscience and Neuropharmacology Research(22), Neuropeptides and Animal Physiology(15), Parathyroid Disorders and Treatments(14), Protein Kinase Regulation and GTPase Signaling(12)

Publications89 total

A novel chemoreactive calcilytic for the potential treatment of autosomal dominant hypocalcemia
Acta Pharmaceutica Sinica B·2025Open Access
Next-Generation Analogues of AC265347 as Positive Allosteric Modulators of the Calcium-Sensing Receptor: Pharmacological Investigation of Structural Modifications at the Stereogenic Centre
International Journal of Molecular Sciences·2025Open Access
Next-Generation Analogues of AC265347 as Positive Allosteric Modulators of the Calcium-Sensing Receptor: Pharmacological Investigation of Structural Modifications at the Stereogenic Centre
Preprints.org·2024Open Access
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
British Journal of Pharmacology·2023· 379 citedOpen Access
CCDC 2259690: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2259688: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2259689: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Direct syntheses of stereoisomers of 3-fluoro GABA and β-fluoroamine analogues of the calcium receptor (CaR) agonists, cinacalcet, tecalcet, fendiline and NPS R-467
Medicinal Chemistry Research·2023· 2 citedOpen Access
Direct syntheses of stereoisomers of 3-fluoro GABA and β-fluoroamine analogues of the calcium receptor (CaR) agonists, cinacalcet, tecalcet, fendilines and NPS R-467
Research Square (Research Square)·2023Open Access
Calcium-sensing receptor in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE·2023Open Access
Calcium-Sensing Receptor Negative Allosteric Modulators Oppose Contraction of Mouse Airways
American Journal of Respiratory Cell and Molecular Biology·2023· 2 cited
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
eLife·2023· 33 citedOpen Access
Author response: Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
2023· 1 citedOpen Access
Fundamental Symmetries, Neutrons, and Neutrinos (FSNN): Whitepaper for the 2023 NSAC Long Range Plan
2023· 8 citedOpen Access
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
2022· 1 citedOpen Access
The Calcium‐Sensing Receptor ( <scp>CaSR</scp> ) in Disease
2022
Author response for "Cell surface calcium‐sensing receptor heterodimers: mutant gene dosage affects Ca &lt;sup&gt;2+&lt;/sup&gt; sensing but not G protein interaction"
2022
Author response for "Cell surface calcium‐sensing receptor heterodimers: mutant gene dosage affects Ca &lt;sup&gt;2+&lt;/sup&gt; sensing but not G protein interaction"
2022
Author response for "Cell surface calcium‐sensing receptor heterodimers: mutant gene dosage affects Ca &lt;sup&gt;2+&lt;/sup&gt; sensing but not G protein interaction"
2022
Personalised medicines for familial hypercalcemia and hyperparathyroidism
Journal of Molecular Endocrinology·2022· 5 citedOpen Access
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Frequent Co-authors

Arthur Christopoulos(34), Patrick M. Sexton(23), Karen J. Gregory(21), Arthur D. Conigrave(15), Andrew N. Keller(7), Shane D. Hellyer(7), Christian C. Felder(6), Lauren T. May(5), Elham Khajehali(5), Tracy M. Josephs(5), Vindhya Nawaratne(4), Irina Kufareva(4), Hee‐Chang Mun(4), Kathy Sengmany(4), Hans Bräuner‐Osborne(3), Debbie L. Hay(3), Anna Davey(3), Anna E. Cook(3), Matthew J. Belousoff(3), Yi-Lynn Liang(3)