Elham Khajehali

Monash University — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index620citations26works0.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Receptor Mechanisms and Signaling(17), Neuroscience and Neuropharmacology Research(11), Nicotinic Acetylcholine Receptors Study(6), Neuropeptides and Animal Physiology(4), Regulation of Appetite and Obesity(3)

Publications26 total

Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M4 mAChR
European Journal of Medicinal Chemistry·2023· 3 citedOpen Access
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
eLife·2023· 33 citedOpen Access
Author response: Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
2023· 1 citedOpen Access
Design, Synthesis and Evaluation of Novel 2-Phenyl-3-(1H-Pyrazol-4-yl)Pyridine Positive Allosteric Modulators for the M4 mAChR
SSRN Electronic Journal·2023Open Access
Inhibitory effects of fluoxetine on the secretion of inflammatory mediators and JAK/STAT3 and JNK/TLR4 gene expression
Molecular Biology Reports·2022· 18 citedOpen Access
M <sub>1</sub> muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease
Science Signaling·2022· 19 citedOpen Access
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics
2022· 1 citedOpen Access
The Inhibitory Effects of Fluoxetine on Secretion of Inflammatory Mediators and Genes Expression of JAK/STAT3 and JNK/TLR4
Research Square (Research Square)·2022Open Access
Investigating Drivers for M <sub>1</sub> Muscarinic Acetylcholine Receptor‐Mediated Adverse Events by M <sub>1</sub> Positive Allosteric Modulators
The FASEB Journal·2022· 1 cited
Structural and Dynamic Mechanisms of Allostery at the M4 Muscarinic Acetylcholine Receptor
SSRN Electronic Journal·2022· 1 citedOpen Access
Activation of M <sub>1</sub> muscarinic receptors reduce pathology and slow progression of neurodegenerative disease
2021· 3 citedOpen Access
Restoring Agonist Function at a Chemogenetically Modified M<sub>1</sub>Muscarinic Acetylcholine Receptor
ACS Chemical Neuroscience·2020· 1 citedOpen Access
Development of Novel 4‐Arylpyridin‐2‐one and 6‐Arylpyrimidin‐4‐one Positive Allosteric Modulators of the M<sub>1</sub> Muscarinic Acetylcholine Receptor
ChemMedChem·2020· 8 citedOpen Access
Negative allosteric modulators of the human calcium‐sensing receptor bind to overlapping and distinct sites within the 7‐transmembrane domain
British Journal of Pharmacology·2019· 20 citedOpen Access
The In Vitro Characterisation of DREADD Agonist 21, a Novel Ligand for Muscarinic DREADD Receptors
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)·2019Open Access
CCDC 1861507: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M<sub>1</sub> mAChR: The Determinants of Allosteric Activity
ACS Chemical Neuroscience·2018· 11 citedOpen Access
Dual Action Calcium-Sensing Receptor Modulator Unmasks Novel Mode-Switching Mechanism
ACS Pharmacology & Translational Science·2018· 16 citedOpen Access
DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs<i>in Vitro</i>and<i>in Vivo</i>
ACS Pharmacology & Translational Science·2018· 185 citedOpen Access
Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor
Biochemical Pharmacology·2018· 22 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Arthur Christopoulos(21), Patrick M. Sexton(16), Céline Valant(15), Andrew B. Tobin(14), Emma T. van der Westhuizen(13), Ben Capuano(9), Katie Leach(8), Craig W. Lindsley(8), Manuela Jörg(8), Peter J. Scammells(8), Wessel A. C. Burger(6), David M. Thal(6), Sophie J. Bradley(5), Colin Molloy(5), Ziva Vuckovic(4), Jinan Wang(4), Vi Pham(4), Jesse I. Mobbs(4), Matthew J. Belousoff(4), Apurba Bhattarai(4)