Michael C. Laufersweiler

Procter & Gamble (United States) — United States

Environmental Science · Physical Sciences

12h-index2.0kcitations20works0.02yr avg
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Research Topics

Effects and risks of endocrine disrupting chemicals(4), Chemical Synthesis and Analysis(4), Pesticide Exposure and Toxicity(3), Animal testing and alternatives(3), Peptidase Inhibition and Analysis(3)

Publications20 total

Letter to the editor
Toxicological Sciences·2022
Threshold of Toxicological Concern: Extending the chemical space by inclusion of a highly curated dataset for organosilicon compounds
Regulatory Toxicology and Pharmacology·2021· 6 citedOpen Access
Bolstering the existing database supporting the non-cancer Threshold of Toxicological Concern values with toxicity data on fragrance-related materials
Regulatory Toxicology and Pharmacology·2020· 35 citedOpen Access
The Threshold of Toxicological Concern (TTC) approach can be applied to organosilicon compounds
Toxicology Letters·2018
Structure activity relationship (SAR) toxicological assessments: The role of expert judgment
Regulatory Toxicology and Pharmacology·2018· 30 cited
Framework for Identifying Chemicals with Structural Features Associated with the Potential to Act as Developmental or Reproductive Toxicants
Chemical Research in Toxicology·2013· 178 cited
Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern
Regulatory Toxicology and Pharmacology·2011· 1.6k cited
Carboxylic Acid-Terminated Hyperbranched Polybenzoxazole and Its Polyarm-Star Block Copolymers
Macromolecules·2009· 5 cited
CCDC 608956: Experimental Crystal Structure Determination
The Cambridge Structural Database·2007Open Access
Synthesis and evaluation of unsaturated caprolactams as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & Medicinal Chemistry·2006· 18 citedOpen Access
Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & Medicinal Chemistry·2006· 14 cited
Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis
Bioorganic & Medicinal Chemistry Letters·2006· 49 citedOpen Access
Synthesis and evaluation of thiazepines as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & Medicinal Chemistry Letters·2006· 16 citedOpen Access
Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & Medicinal Chemistry Letters·2006· 6 citedOpen Access
Synthesis and evaluation of novel 8,6-fused bicyclic peptidomimetic compounds as interleukin-1β converting enzyme inhibitors
Bioorganic & Medicinal Chemistry Letters·2005· 20 citedOpen Access
Synthesis and evaluation of tricyclic pyrrolopyrimidinones as dipeptide mimetics: Inhibition of interleukin-1β-converting enzyme
Bioorganic & Medicinal Chemistry Letters·2005· 12 citedOpen Access
Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1β synthesis
Bioorganic & Medicinal Chemistry Letters·2005· 21 citedOpen Access
Potent and Selective Carboxylic Acid-Based Inhibitors of Matrix Metalloproteinases
Journal of Medicinal Chemistry·2001· 51 citedOpen Access
Stadtklimatologie im ländlichen Raum
Standort·1997
Stadtklimatologie im ländlichen Raum
Standort·1997

Frequent Co-authors

Steven V. O’Neil(9), Yili Wang(9), Kofi A. Oppong(8), Christopher D. Ellis(8), David L. Soper(8), John A. Wos(8), Amy N. Fancher(8), Maureen K. Suchanek(7), Biswanath De(6), Mark W. Baize(6), Richard L. Wang(6), Thomas P. Demuth(5), Wei Lü(5), Karen Blackburn(3), George P. Daston(3), Shengde Wu(3), Cathy Lester(3), Thomas Demuth(3), Justin Sheville(3), Susan P. Felter(2)