Sebastian Markmiller

University of California, San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index3.2kcitations28works0.02yr avg
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Research Topics

RNA Research and Splicing(14), Amyotrophic Lateral Sclerosis Research(8), RNA modifications and cancer(6), Genetic Neurodegenerative Diseases(5), Endoplasmic Reticulum Stress and Disease(5)

Publications28 total

VPS13A and VPS13C influence lipid droplet abundance
2022· 3 citedOpen Access
APEX Proximity Labeling of Stress Granule Proteins
Methods in molecular biology·2022· 13 citedOpen Access
VPS13A and VPS13C Influence Lipid Droplet Abundance
Contact·2022· 22 citedOpen Access
Huntington’s disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization
Journal of Clinical Investigation·2021· 64 citedOpen Access
Large-scale tethered function assays identify factors that regulate mRNA stability and translation
Nature Structural & Molecular Biology·2020· 126 citedOpen Access
Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
Nature Communications·2020· 2 citedOpen Access
Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
Nature Communications·2020· 55 citedOpen Access
Persistent mRNA Localization Defects and Cell Death in ALS Neurons Caused by Transient Cellular Stress
SSRN Electronic Journal·2020· 4 citedOpen Access
Phenotypic Suppression of ALS/FTD-Associated Neurodegeneration Highlights Mechanisms of Dysfunction
Journal of Neuroscience·2019· 16 citedOpen Access
Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
Neuron·2019· 263 citedOpen Access
Active Protein Neddylation or Ubiquitylation Is Dispensable for Stress Granule Dynamics
Cell Reports·2019· 62 citedOpen Access
Modulation of RNA-dependent interactions in stress granules prevents persistent TDP-43 accumulation in ALS/FTD
2018· 1 cited
Early developmental arrest and impaired gastrointestinal homeostasis in U12-dependent splicing-defective <i>Rnpc3</i>-deficient mice
RNA·2018· 29 citedOpen Access
Active protein neddylation or ubiquitylation is dispensable for stress granule dynamics
2018· 4 citedOpen Access
Context‐dependent and Disease‐specific Diversity in Stress Granules Formed from Pre‐existing Protein Interactions
The FASEB Journal·2018· 4 cited
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
Cell·2018· 929 citedOpen Access
Active Protein Neddylation or Ubiquitylation is Dispensable for Stress Granule Dynamics
SSRN Electronic Journal·2018· 1 citedOpen Access
TMOD-42. CRISPR/Cas9-EDITED HUMAN NEURAL STEM CELLS GIVE RISE TO BRAIN TUMORS RESEMBLING GLIOBLASTOMAS
Neuro-Oncology·2017Open Access
Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9
Cell·2017· 254 citedOpen Access
Proximity labeling reveals an extensive steady-state stress granule interactome and insights to neurodegeneration
2017· 1 citedOpen Access
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Frequent Co-authors

G Yeo(21), Eric J. Bennett(8), Mario Dejung(6), Mark Y. Fang(5), Éric Lécuyer(5), Joan K. Heath(5), Kari L. Server(4), En‐Ching Luo(4), Graham J. Lieschke(4), Sahar Soltanieh(3), Raymond Mak(3), Wenhao Jin(3), Florian Krach(3), Anindya Sen(3), Mark W. Kankel(3), John Ravits(3), Anthony Q. Vu(3), Isaac A. Chaim(3), Shashank Sathe(3), Maria-Cristina Keightley(3)