Nicolas Willand

Inserm — France

Medicine · Health Sciences

25h-index2.0kcitations96works0.92yr avg
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Research Topics

Tuberculosis Research and Epidemiology(29), Cancer therapeutics and mechanisms(25), Biochemical and Molecular Research(16), Chemical Synthesis and Analysis(14), Antibiotic Resistance in Bacteria(8)

Publications96 total

In vitro pharmacokinetics and pharmacodynamics of the diarylquinoline TBAJ-587 and its metabolites against Mycobacterium tuberculosis
2025
Exploiting Vitamin B6 Dependency: BVL3572S Inhibits HisC and AlaA to Kill <i>Mycobacterium tuberculosis</i>
2025Open Access
Exploiting Vitamin B6 Dependency: BVL3572S Inhibits HisC and AlaA to Kill Mycobacterium tuberculosis
SSRN Electronic Journal·2025Open Access
Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase
iScience·2024· 4 citedOpen Access
Small molecule MarR modulators potentiate metronidazole antibiotic activity in aerobic E. coli by inducing activation by the nitroreductase NfsA
Journal of Biological Chemistry·2024· 1 citedOpen Access
Evaluation of critical parameters in the hollow‐fibre system for tuberculosis: A case study of moxifloxacin
British Journal of Clinical Pharmacology·2024· 1 citedOpen Access
Crystal structure of the Mycobacterium tuberculosis VirS regulator reveals its interaction with the lead compound SMARt751
Journal of Structural Biology·2024Open Access
Biocatalytic Regioselective <i>O</i>‐acylation of Sesquiterpene Lactones from Chicory: A Pathway to Novel Ester Derivatives
ChemBioChem·2024· 1 citedOpen Access
Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae
EMBO Molecular Medicine·2023· 20 citedOpen Access
Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against Mycobacterium tuberculosis
International Journal of Molecular Sciences·2023· 2 citedOpen Access
CCDC 2226330: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump
European Journal of Medicinal Chemistry·2023· 10 citedOpen Access
Biocatalytic approach to the chemoselective acylation of sesquiterpene lactones from chicory: a pathway to novel ester derivatives
2023· 1 citedOpen Access
Biocatalytic approach to the chemoselective acylation of sesquiterpene lactones from chicory: a pathway to novel ester derivatives
2023· 1 citedOpen Access
Recent advances in Fragment-based strategies against tuberculosis
European Journal of Medicinal Chemistry·2023· 8 citedOpen Access
A Three-Step Process to Isolate Large Quantities of Bioactive Sesquiterpene Lactones from Cichorium intybus L. Roots and Semisynthesis of Chicory STLs Standards
Pharmaceuticals·2023· 12 citedOpen Access
Antibiotics with novel mode of action as new weapons to fight antimicrobial resistance
European Journal of Medicinal Chemistry·2023· 31 citedOpen Access
A Three-step Process to Isolate Large Quantities of Bioactive Sesquiterpene Lactones from &lt;em&gt;Cichorium intybus&lt;/em&gt; L. Roots and Semi-synthesis of Chicory STLs Standards
Preprints.org·2023· 4 citedOpen Access
A Three-step Process to Isolate Large Quantities of Bioactive Sesquiterpene Lactones from &lt;em&gt;Cichorium intybus&lt;/em&gt; L. Roots and Semi-synthesis of Chicory STLs Standards
Preprints.org·2023· 1 citedOpen Access
CCDC 2215399: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
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Frequent Co-authors

Benoît Déprez(39), Alain R. Baulard(24), Marion Flipo(21), Baptiste Villemagne(12), Florence Leroux(12), René Wintjens(11), Priscille Brodin(11), Catherine Piveteau(10), Alexandre Wohlkönig(9), Rebecca Deprez‐Poulain(8), Camille Locht(8), Matthieu Desroses(7), Vincent Villeret(7), Martin Moune(7), Rosangela Frita(6), Adrien Herlédan(6), Jean‐Claude Gesquière(6), Ruxandra Gref(5), Patrick Toto(5), Ruben C. Hartkoorn(5)