Yi Sun

Children's Hospital of Philadelphia — United States

Immunology and Microbiology · Life Sciences

19h-index1.4kcitations56works5.22yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Immunotherapy and Immune Responses(14), T-cell and B-cell Immunology(12), vaccines and immunoinformatics approaches(9), Monoclonal and Polyclonal Antibodies Research(5), Immune Cell Function and Interaction(5)

Publications56 total

Atomically accurate de novo design of antibodies with RFdiffusion
Nature·2025· 24 citedOpen Access
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity
2025Open Access
Observation of SAM-VI Riboswitch Dynamics Using Single-Molecule FRET
Biomolecules·2025Open Access
Morus alba L. alleviates influenza viral pneumonia. Evidences of its mechanism of action
Phytomedicine·2025· 1 citedOpen Access
CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading
Proceedings of the National Academy of Sciences·2025· 7 citedOpen Access
Silver-adsorbed Ti<sub>0.87</sub>O<sub>2</sub> nanosheets and UV irradiation synergistically improve the energy storage performance of polyvinylidene fluoride-based nanocomposites
Journal of Materials Chemistry C·2025
Targeting peptide antigens using a multiallelic MHC I-binding system
Nature Biotechnology·2024· 20 citedOpen Access
CryoEM structure of an MHC-I/TAPBPR peptide bound intermediate reveals the mechanism of antigen proofreading
2024Open Access
Abstract 2443 Expanding the applications of open MHC-I molecules for enhanced thermostability and peptide loading to HLA-A*11:01 and HLA-C*07:02 allotypes
Journal of Biological Chemistry·2024Open Access
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes
Biophysical Journal·2024
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition
Nature Communications·2023· 11 citedOpen Access
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
Science Immunology·2023· 17 citedOpen Access
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
Proceedings of the National Academy of Sciences·2023· 30 citedOpen Access
Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion
2023· 1 citedOpen Access
Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules
The Journal of Immunology·2023Open Access
Xeno-interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes
The Journal of Immunology·2023Open Access
Universal, open MHC-I for rapid ligand loading and enhanced complex stability across classical and non-classical allotypes
The Journal of Immunology·2023Open Access
Aurantimonas marianensis sp. nov., isolated from deep-sea sediment of the Mariana Trench
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY·2023
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
2023· 3 citedOpen Access
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes
Science Advances·2023· 20 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Nikolaos G. Sgourakis(15), Michael C. Young(9), Julia N. Danon(8), Georgia Papadaki(8), Max B. Kelz(5), Hau V. Truong(5), George M. Burslem(5), S. K. Gupta(4), Trenton J. Winters(4), Leena Mallik(4), Tyler J. Florio(4), Jason T. Moore(3), Zixuan Wang(3), Stephen C. Peiper(3), Gladys E. Deibler(3), Claire H. Woodward(3), John M. Maris(3), Christine A. Devlin(3), Erik Procko(3), Devin Dersh(3)