Leena Mallik

Children's Hospital of Philadelphia — United States

Immunology and Microbiology · Life Sciences

10h-index288citations20works11.02yr avg
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Research Topics

Immunotherapy and Immune Responses(5), Photosynthetic Processes and Mechanisms(3), Metal-Catalyzed Oxygenation Mechanisms(3), vaccines and immunoinformatics approaches(3), T-cell and B-cell Immunology(2)

Publications20 total

CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading
Proceedings of the National Academy of Sciences·2025· 7 citedOpen Access
Targeting peptide antigens using a multiallelic MHC I-binding system
Nature Biotechnology·2024· 20 citedOpen Access
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
Journal of Medicinal Chemistry·2024· 17 cited
CryoEM structure of an MHC-I/TAPBPR peptide bound intermediate reveals the mechanism of antigen proofreading
2024Open Access
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
Science Immunology·2023· 17 citedOpen Access
Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P
Journal of Biological Chemistry·2023· 5 citedOpen Access
Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion
2023· 1 citedOpen Access
The Photoactive Excited State of the B<sub>12</sub>-Based Photoreceptor CarH
The Journal of Physical Chemistry B·2020· 35 citedOpen Access
Radical Tropolone Biosynthesis
2020· 17 citedOpen Access
Radical Tropolone Biosynthesis
2020· 4 citedOpen Access
Structure of non-heme iron enzyme TropC: Radical tropolone biosynthesis
2020
Substrate Promiscuity of a Paralytic Shellfish Toxin Amidinotransferase
ACS Chemical Biology·2020· 22 citedOpen Access
SxtG an amidinotransferase from the Microseira wollei in Saxitoxin biosynthetic pathway
2019
Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1
Molecular and Cellular Biology·2016· 10 citedOpen Access
Using Protein Dimers to Maximize the Protein Hybridization Efficiency with Multisite DNA Origami Scaffolds
PLoS ONE·2015· 9 citedOpen Access
Electron Microscopic Visualization of Protein Assemblies on Flattened DNA Origami
ACS Nano·2015· 26 citedOpen Access
Myo1c, an unconventional motor that maintains glomerular filtration function
The FASEB Journal·2013
APOL1 Null Alleles from a Rural Village in India Do Not Correlate with Glomerulosclerosis
PLoS ONE·2012· 85 citedOpen Access
Solution Structure Analysis of Cytoplasmic Domain of Podocyte Protein Neph1 Using Small/Wide Angle X-ray Scattering (SWAXS)
Journal of Biological Chemistry·2012· 13 citedOpen Access
Understanding the solution structure of nephi and z0 1 complex from kidney s filtration assembly view point
INFLIBNET·2012

Frequent Co-authors

Markos Koutmos(7), Alison R. H. Narayan(5), Yi Sun(5), Nikolaos G. Sgourakis(5), Deepak Nihalani(4), Yogendra Singh Rathore(4), Lawrence B. Holzman(4), Ashish(3), Daniel Hwang(3), Georgia Papadaki(3), Michael C. Young(3), Kimia Dasteh Goli(3), Tyler J. Doyon(3), Ehtesham Arif(3), Georgios Skiniotis(2), April L. Lukowski(2), Kevin Skinner(2), Troy Wymore(2), Paul M. Zimmerman(2), Tyler J. Florio(2)