Nicole Borth

Austrian Centre of Industrial Biotechnology (Austria) — Austria

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index6.9kcitations224works2.12yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(144), CRISPR and Genetic Engineering(67), Virus-based gene therapy research(36), Microbial Metabolic Engineering and Bioproduction(29), Protein purification and stability(24)

Publications222 total

CRISPR-based precise methylation of specific FUT8 promoter regions allows isolation of CHO cells with a fine-tuned glycoprofile
Journal of Biotechnology·2026Open Access
MCBO: Mammalian Cell Bioprocessing Ontology, A Hub-and-Spoke, IOF-Anchored Application Ontology
2026Open Access
What do you most hope we will achieve with mammalian synthetic biology within the next decade?
Cell Systems·2025
Comparative Analysis of HEK293 Genomic Variability
Biotechnology and Bioengineering·2025Open Access
Human diamine oxidase undergoes transcytosis and colocalizes with the plasma membrane monoamine transporter indicating intracellular histamine degradation
European Journal of Cell Biology·2025Open Access
A genome-scale CRISPR deletion screen in Chinese hamster ovary cells reveals essential regions of the coding and non-coding genome
Metabolic Engineering·2025· 4 citedOpen Access
Low-cost food-grade alternatives for serum albumins in FBS-free cell culture media
Scientific Reports·2025· 9 citedOpen Access
Overcoming lentiviral delivery limitations in hard-to-transduce suspension cells for genome-wide CRISPR screening
2025· 1 citedOpen Access
A genome-scale CRISPR deletion screen in Chinese Hamster Ovary cells reveals essential regions of the coding and non-coding genome
2025Open Access
Stepwise activation of gene copies results in higher final titers of subclones compared to immediate integration of the full set of active copies
New Biotechnology·2025· 2 citedOpen Access
Large-scale transcriptomics analysis reveals a novel stress biomarker in CHO cells producing difficult to express mAbs
Scientific Reports·2025· 4 citedOpen Access
Nitric oxide is an irreversible human diamine oxidase inhibitor
Free Radical Research·2025Open Access
Characterization of large transgene integrations in Chinese hamster ovary cells using a bioengineered mammalian transposase
Biotechnology Progress·2025Open Access
Fantastic genes and where to find them expressed in CHO
Computational and Structural Biotechnology Journal·2025· 5 citedOpen Access
Corrigendum to “Manipulating gene expression levels in mammalian cell factories: An outline of synthetic molecular toolboxes to achieve multiplexed control” [New Biotechnol 79 (2024) 1–19]
New Biotechnology·2024Open Access
Molecular biomarkers identification and applications in CHO bioprocessing
Journal of Biotechnology·2024· 4 citedOpen Access
Combined approach of selective and accelerated cloning for microfluidic chip‐based system increases clone specific productivity
Biotechnology Journal·2024· 7 citedOpen Access
Manipulating gene expression levels in mammalian cell factories: An outline of synthetic molecular toolboxes to achieve multiplexed control
New Biotechnology·2023· 21 citedOpen Access
Glutamine synthetase (GS) knockout (KO) using CRISPR/Cpf1 diversely enhances selection efficiency of CHO cells expressing therapeutic antibodies
Scientific Reports·2023· 16 citedOpen Access
LncRNA analysis of mAb producing CHO clones reveals marker and engineering potential
Metabolic Engineering·2023· 11 citedOpen Access
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Frequent Co-authors

Matthias Hackl(12), Vaibhav Jadhav(12), Johannes Grillari(11), Martina Baumann(10), Renate Kunert(8), Michael Hanscho(7), Karina Brinkrolf(7), Diethard Mattanovich(6), Hermann Katinger(6), Oliver Rupp(6), Alexander Goesmann(6), Alfred Pühler(6), Juan A. Hernández Bort(6), Michael J. Betenbaugh(5), Thomas Noll(5), Jürgen Zanghellini(4), Lars K. Nielsen(4), Nathan E. Lewis(4), Norbert Auer(4), Daniela Huber(4)