Palak Panchal

Memorial Sloan Kettering Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index894citations32works4.82yr avg
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Research Topics

Heat shock proteins research(8), Computational Drug Discovery Methods(7), Endoplasmic Reticulum Stress and Disease(5), Protein Structure and Dynamics(4), HIV/AIDS Research and Interventions(4)

Publications32 total

Mapping Dysfunctional Protein-Protein Interactions in Disease
Journal of Visualized Experiments·2025Open Access
TRENDS AND PREVALENCE OF SYPHILIS INFECTION AMONGST VOLUNTARY BLOOD DONORS AT A STAND-ALONE BLOOD CENTRE-AN ANALYSIS
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH·2025
Systems-Level Interactome Mapping Reveals Actionable Protein Network Dysregulation Across the Alzheimer's Disease Spectrum
2025· 1 citedOpen Access
Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation
Nature Communications·2024· 22 citedOpen Access
Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative Disorders
Biomedicines·2024· 5 citedOpen Access
Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
2024· 1 citedOpen Access
Unraveling the Mechanism of Epichaperome Modulation by Zelavespib: Biochemical Insights on Target Occupancy and Extended Residence Time at the Site of Action
Biomedicines·2023· 11 citedOpen Access
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
Nature Communications·2023· 40 citedOpen Access
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view
Structure·2023· 33 citedOpen Access
Use of Native-PAGE for the Identification of Epichaperomes in Cell Lines
Methods in molecular biology·2023· 7 citedOpen Access
How Aberrant <i>N</i> -Glycosylation Can Alter Protein Functionality and Ligand Binding: an Atomistic View
2022Open Access
Synthesis of 124I-labeled epichaperome probes and assessment in visualizing pathologic protein-protein interaction networks in tumor bearing mice
STAR Protocols·2022· 5 citedOpen Access
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
Communications Biology·2021· 23 citedOpen Access
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
Nature Communications·2021· 33 citedOpen Access
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia
npj Precision Oncology·2021· 36 citedOpen Access
Metadata record for the manuscript: Targeting the Epichaperome As an Effective Precision Medicine Approach in a Novel PML-SYK Fusion Acute Myeloid Leukemia
Figshare·2021· 1 citedOpen Access
Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
Cell Reports·2020· 59 citedOpen Access
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction
Nature Communications·2020· 82 citedOpen Access
Experience with antiretroviral electronic adherence monitoring among young African American men who have sex with men living with HIV: findings to inform a triaged real-time alert intervention
AIDS Care·2020· 3 citedOpen Access
Biomarker based targeting of the epichaperome as a novel therapeutic approach for Multiple Myeloma (MM)
Clinical Lymphoma Myeloma & Leukemia·2019
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Frequent Co-authors

Gabriela Chiosis(22), Sahil Sharma(15), Anna Rodina(14), Chander Singh Digwal(13), Pengrong Yan(10), Hediye Erdjument‐Bromage(9), Suhasini Joshi(9), Thomas A. Neubert(8), Stephen D. Ginsberg(8), Tony Taldone(7), Adriana Corben(7), Tanaya Roychowdhury(7), Mark S. Dworkin(7), Nagavarakishore Pillarsetty(6), Tai Wang(5), Shanu Modi(5), Mónica L. Guzmán(5), Elisa de Stanchina(5), Sadık Bay(5), Mary L. Alpaugh(4)