Mam Y. Mboge

University of Florida — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index834citations25works6.02yr avg
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Research Topics

Enzyme function and inhibition(17), Synthesis and Catalytic Reactions(10), Chemical Reactions and Mechanisms(7), Nitric Oxide and Endothelin Effects(4), Cholinesterase and Neurodegenerative Diseases(4)

Publications25 total

Disruption of the Physical Interaction Between Carbonic Anhydrase IX and the Monocarboxylate Transporter 4 Impacts Lactate Transport in Breast Cancer Cells
International Journal of Molecular Sciences·2024· 6 citedOpen Access
Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer
Journal of Medicinal Chemistry·2021· 31 citedOpen Access
The not-so-sweet side of sugar: Influence of the microenvironment on the processes that unleash cancer
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2020· 5 citedOpen Access
β-caryophyllene enhances the transcriptional upregulation of cholesterol biosynthesis in breast cancer cells
Current Topics in Biochemical Research·2019· 8 citedOpen Access
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells
Biochemical Journal·2019· 35 cited
β-Caryophyllene Enhances the Transcriptional Upregulation of Cholesterol Biosynthesis in Breast Cancer Cells
2019· 1 citedOpen Access
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells
2018· 5 citedOpen Access
Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition
PLoS ONE·2018· 46 citedOpen Access
Biophysical, Biochemical, and Cell Based Approaches Used to Decipher the Role of Carbonic Anhydrases in Cancer and to Evaluate the Potency of Targeted Inhibitors
International Journal of Medicinal Chemistry·2018· 4 citedOpen Access
Differential expression and function of CAIX and CAXII in breast cancer: A comparison between tumorgraft models and cells
PLoS ONE·2018· 68 citedOpen Access
Abstract 1436: Beta-caryophyllene regulates lipid biosynthesis in breast cancer cells
Cancer Research·2018
Abstract 2102: UFH-001: A novel triple-negative, CAIX-positive cell line for small-molecule targeting of human breast cancer
Cancer Research·2018
Cancer Drug Development of Carbonic Anhydrase Inhibitors beyond the Active Site
Molecules·2018· 148 citedOpen Access
UFH-001 cells: A novel triple negative, CAIX-positive, human breast cancer model system
Cancer Biology & Therapy·2018· 14 citedOpen Access
Carbonic Anhydrases: Role in pH Control and Cancer
Metabolites·2018· 269 citedOpen Access
Abstract 5936: Comparison of carbonic anhydrase & activity between triple-negative & luminal breast cancer cells
Cancer Research·2017
Abstract 2931: Targeting membrane-bound carbonic anhydrases in breast cancer to intervene in the metastatic phenotype
Cancer Research·2017
Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides
European Journal of Medicinal Chemistry·2017· 66 citedOpen Access
Advances in Anti-Cancer Drug Development Targeting Carbonic Anhydrase IX and XII
BENTHAM SCIENCE PUBLISHERS eBooks·2016· 57 citedOpen Access
Abstract B25: Characterization, targeting, and modulation of carbonic anhydrase IX activity for the development of small-molecule inhibitors to treat triple-negative breast cancer
Cancer Research·2016
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Frequent Co-authors

Susan C. Frost(20), Robert McKenna(16), Zhijuan Chen(9), Fabrizio Carta(7), Brian P. Mahon(6), Lingbao Ai(6), Coy D. Heldermon(6), Claudiu T. Supuran(6), Christopher J. Frost(6), Chingkuang Tu(5), Alyssa Wolff(5), Kevin D. Brown(4), John V. Mathias(4), Carrie L. Lomelino(3), Murat Bozdağ(3), Adam Bullock(3), Julie Davila(3), Srishti Singh(2), Nicole Lamas(2), Daniel Khokhar(2)