James L. Bullington

Johnson & Johnson (United States) — United States

Chemistry · Physical Sciences

10h-index369citations15works0.02yr avg
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Research Topics

Synthesis and biological activity(3), Adenosine and Purinergic Signaling(3), Marine Sponges and Natural Products(3), Melanoma and MAPK Pathways(2), Cyclopropane Reaction Mechanisms(2)

Publications15 total

In Vivo Characterization of a Dual Adenosine A<sub>2A</sub>/A<sub>1</sub> Receptor Antagonist in Animal Models of Parkinson’s Disease
Journal of Medicinal Chemistry·2010· 54 citedOpen Access
Methylene amine substituted arylindenopyrimidines as potent adenosine A2A/A1 antagonists
Bioorganic & Medicinal Chemistry Letters·2010· 24 citedOpen Access
Optimization of arylindenopyrimidines as potent adenosine A2A/A1 antagonists
Bioorganic & Medicinal Chemistry Letters·2010· 12 citedOpen Access
Inhibitors of unactivated p38 MAP kinase
Bioorganic & Medicinal Chemistry Letters·2006· 11 citedOpen Access
Regioselective Preparation of 2‐Substituted 3,4‐Diaryl Pyrroles: A Concise Total Synthesis of Ningalin B.
ChemInform·2003Open Access
Regioselective Preparation of 2-Substituted 3,4-Diaryl Pyrroles:  A Concise Total Synthesis of Ningalin B
The Journal of Organic Chemistry·2002· 107 cited
Pyridinylimidazole Based p38 MAP Kinase Inhibitors
Current Topics in Medicinal Chemistry·2002· 57 cited
ChemInform Abstract: Stereoselectivity in the Rhodium(II) Acetate Catalyzed Cyclopropanations of 2‐Diazo‐1‐indanone with Styrenes.
ChemInform·2000
Stereoselectivity in the rhodium(II) acetate catalysed cyclopropanations of 2-diazo-1-indanone with styrenes
Tetrahedron Letters·2000· 18 cited
ChemInform Abstract: The Development of Novel and Selective p56<sup>Ick</sup> Tyrosine Kinase Inhibitors.
ChemInform·1999
ChemInform Abstract: Synthesis of Spiro[2H‐indole‐2,1′‐1H‐isoindole]‐3,3′‐diones (V), Spiro[1H‐isobenzofuran‐1,2′‐2H‐indole]‐3,3′‐diones (IV), and Spiro[benzofuran‐2,1′‐isobenzofuran]‐3,3′‐diones (X) via Transannular Reactions of Eight‐Membered Ring Intermediates.
ChemInform·1998· 1 cited
The development of novel and selective p56lck tyrosine kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·1998· 13 citedOpen Access
Synthesis of spiro[2<i>H</i>‐indole‐2,1′‐1<i>H</i>‐isoindole]‐3,3′‐diones, spiro[1<i>H</i>‐isobenzofuran‐1,2′‐2<i>H</i>‐indole]‐3,3′‐diones and spiro[benzofuran‐2,1′‐isobenzofuran]‐3,3′‐diones <i>via</i> transannular reactions of eight membered ring intermediates
Journal of Heterocyclic Chemistry·1998· 16 cited
ChemInform Abstract: Synthesis of Tetrahydroindeno(1,2‐b)indol‐10‐ones and Their Rearrangement to (2)Benzopyrano(4,3‐b)indol‐5‐ones.
ChemInform·1994
Synthesis of tetrahydroindeno[1,2-b]indol-10-ones and their rearrangement to [2]benzopyrano[4,3-b]indol-5-ones
The Journal of Organic Chemistry·1993· 56 cited

Frequent Co-authors

John H. Dodd(8), Paul Jackson(7), Kenneth C. Rupert(6), D.W.R. Hall(4), Geoffrey R. Heintzelman(4), Ronald K. Russell(4), Brian C. Shook(3), Stefanie Rassnick(3), Lori Westover(3), Devraj Chakravarty(3), Shawn Branum(3), Kenneth M. Wells(3), Sandra Damon(3), Scott Youells(3), Xun Li(3), Kenneth J. Rhodes(3), John J. Siekierka(3), Russell R. Wolff(2), Derek A. Beauchamp(2), Keith T. Demarest(2)