Robert H. Grafström

Bristol-Myers Squibb (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index1.6kcitations34works0.02yr avg
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Research Topics

Biochemical and Molecular Research(9), DNA and Nucleic Acid Chemistry(7), DNA Repair Mechanisms(6), Bacteriophages and microbial interactions(6), HIV/AIDS drug development and treatment(5)

Publications34 total

The Amyloid-β Rise and γ-Secretase Inhibitor Potency Depend on the Level of Substrate Expression
Journal of Biological Chemistry·2008· 66 citedOpen Access
Synthesis and Biological Evaluation of 1-Aryl-4,5-dihydro-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidin-4-one Inhibitors of Cyclin-Dependent Kinases
Journal of Medicinal Chemistry·2004· 100 citedOpen Access
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3
Bioorganic & Medicinal Chemistry Letters·2003· 38 citedOpen Access
Identification of Peptide Substrates for Human MMP-11 (Stromelysin-3) Using Phage Display
Journal of Biological Chemistry·2003· 54 citedOpen Access
Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 3. Structure Activity Relationships at C3
Journal of Medicinal Chemistry·2002· 47 citedOpen Access
Identification of selective inhibitors of cyclin dependent kinase 4
Bioorganic & Medicinal Chemistry Letters·2001· 48 citedOpen Access
Quinazolines as cyclin dependent kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2001· 85 citedOpen Access
A cyclin D1/cyclin-dependent kinase 4 binding site within the C domain of the retinoblastoma protein.
PubMed·2001· 48 cited
Defining the substrate specificity of cdk4 kinasecyclin D1 complex
Carcinogenesis·1999· 47 citedOpen Access
Genetically Engineered Bacteria to Identify and Produce Anti-Viral Agents
Advances in experimental medicine and biology·1992
The DNA binding properties of the MutL protein isolated from<i>Escherichia coli</i>
Nucleic Acids Research·1991· 60 cited
Novel bacteriological assay for detection of potential antiviral agents
Antimicrobial Agents and Chemotherapy·1990· 13 cited
Methyl-directed repair of frameshift heteroduplexes in cell extracts from Escherichia coli
Journal of Bacteriology·1989· 32 citedOpen Access
In vivo studies of repair of 2-aminopurine in Escherichia coli
Journal of Bacteriology·1988· 10 citedOpen Access
Mechanism of Thymineless Death
Advances in experimental medicine and biology·1986· 63 cited
The Repair of Pyrimidine Dimers Via a DNA-Glycosylase Mechanism
1986· 2 cited
The characteristics of DNA methytation in an<i>in vitro</i>DNA synthesizing system from mouse fibroblasts
Nucleic Acids Research·1985· 34 citedOpen Access
DNA Methylation: DNA Replication and Repair
Springer series in molecular biology·1984· 7 cited
Cloning of mutH and identification of the gene product
Gene·1983· 16 cited
Cloning, identification and partial purification of mutH gene product
1983· 1 cited
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Frequent Co-authors

Lawrence I. Grossman(6), Catherine R. Burton(6), Steven P. Seitz(6), Pamela A. Benfield(5), George L. Trainor(5), Sarah Cox(5), Nancy L. Shaper(4), Charles W. L. Hill(4), Ben Tseng(4), Mehran Goulian(4), Jay A. Markwalder(3), Michael D. Boisclair(3), Chong‐Hwan Chang(3), Lisa M. Sisk(3), J.K. Muckelbauer(3), John F. Boylan(3), Angela Smallwood(3), William L. Steinhart(3), William A. Haseltine(2), Marc R. Arnone(2)