Laura J. Janke

St. Jude Children's Research Hospital — United States

Medicine · Health Sciences

34h-index5.3kcitations188works0.82yr avg
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Research Topics

Acute Myeloid Leukemia Research(56), Acute Lymphoblastic Leukemia research(27), Chronic Myeloid Leukemia Treatments(25), Drug Transport and Resistance Mechanisms(17), Epigenetics and DNA Methylation(16)

Publications188 total

FBXO11 suppression rewires an NPM1-centered interactome influencing the progression of myelodysplastic syndrome
Journal of Clinical Investigation·2026Open Access
Data from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 8 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 3 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplementary Tables S1-S7 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 1 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 5 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 4 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 2 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 6 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Supplemental Figure 7 from Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
2026Open Access
Carbohydrate adaptation drives liver-brain axis maturation
2025
Menin inhibition as a new therapeutic option for the myeloproliferative neoplasms
Blood·2025
UBTF tandem duplications generate a nuclear export signal motif that drives an XPO1 dependency in leukemia
Blood·2025
Characterizing the In Vivo impact of inflammation on Samd9l hematopoietic phenotypes.
Blood·2025Open Access
Tandem Duplications in <i>UBTF</i> Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency
Blood Cancer Discovery·2025· 1 citedOpen Access
Temporal genetic switches define the constraints of finite Treg repertoires 9018
The Journal of Immunology·2025Open Access
EXTH-20. Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
Neuro-Oncology·2025
EPCO-05. AN ONCOGENIC PHOTORECEPTOR PROGRAM UNIFIES DISTINCT CENTRAL NERVOUS SYSTEM TUMORS
Neuro-Oncology·2025Open Access
Supplementary Figure S3 from KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in &lt;i&gt;NUP98&lt;/i&gt;-Rearranged Acute Myeloid Leukemia
2025Open Access
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Frequent Co-authors

Charles G. Mullighan(11), Ilaria Iacobucci(9), Douglas R. Green(7), Debbie Payne-Turner(7), Lie Li(7), Mary V. Relling(7), Ching‐Hon Pui(6), Peter Vogel(6), Chunxu Qu(6), Kathryn G. Roberts(6), Taosheng Chen(6), Kirsten Dickerson(5), Beisi Xu(5), Stephen P. Hunger(5), Hiroto Inaba(5), Christopher P. Dillon(4), Thirumala‐Devi Kanneganti(4), Zhaohui Gu(4), Mignon L. Loh(4), Stanley Pounds(4)