Bruce S. Foster

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index837citations22works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(7), Oxidative Organic Chemistry Reactions(5), Synthesis and Biological Evaluation(5), Asymmetric Synthesis and Catalysis(4), Chemical Synthesis and Reactions(4)

Publications22 total

Diastereoselective Reductive Amination of Aryl Trifluoromethyl Ketones and α‐Amino Esters.
ChemInform·2007
Diastereoselective Reductive Amination of Aryl Trifluoromethyl Ketones and α‐Amino Esters
Angewandte Chemie International Edition·2007· 65 cited
Diastereoselective Reductive Amination of Aryl Trifluoromethyl Ketones and α‐Amino Esters
Angewandte Chemie·2007· 15 cited
The Expedient Synthesis of 4,2‘-Difluoro-5‘-(7-trifluoromethyl- imidazo[1,2<i>-a</i>]pyrimidin-3-yl)biphenyl-2-carbonitrile, a GABA α2/3 Agonist
Organic Process Research & Development·2006· 45 cited
Palladium-Catalyzed Regioselective Arylation of Imidazo[1,2-<i>b</i>][1,2,4]triazine:  Synthesis of an α<sub>2/</sub><sub>3</sub>-Selective GABA Agonist
The Journal of Organic Chemistry·2005· 64 cited
An Asymmetric Synthesis of 3‐Aryl‐1,4‐oxazin‐2‐ones: Synthesis of a Key Intermediate of an NK<sub>1</sub> Receptor Antagonist.
ChemInform·2003
An Asymmetric Synthesis of 3-Aryl-1,4-oxazin-2-ones: Synthesis of a Key Intermediate of an NK1 Receptor Antagonist
Heterocycles·2002· 9 citedOpen Access
Practical Asymmetric Synthesis of an Endothelin Receptor Antagonist
The Journal of Organic Chemistry·1999· 96 cited
ChemInform Abstract: The Behavior of Indene Oxide in the Ritter Reaction: A Simple Route to cis‐Aminoindanol.
ChemInform·1995· 1 cited
The behavior of indene oxide in the ritter reaction: A simple route to cis-aminoindanol
Tetrahedron Letters·1995· 130 cited
ChemInform Abstract: Efficient Synthesis of Losartan, a Nonpeptide Angiotensin II Receptor Antagonist.
ChemInform·1995
Efficient Synthesis of Losartan, A Nonpeptide Angiotensin II Receptor Antagonist
The Journal of Organic Chemistry·1994· 191 cited
ChemInform Abstract: Stannylquinones. Synthesis and Utilization as Quinone Carbanion Synthetic Equivalents.
ChemInform·1991
Stannylquinones. Synthesis and utilization as quinone carbanion synthetic equivalents
Journal of the American Chemical Society·1990· 39 cited
ChemInform Abstract: Metal Mediated Routes to 5‐Membered Rings
ChemInform·1988
ChemInform Abstract: A Stereoselective, Palladium‐Catalyzed Route to 4‐Oxygenated 5‐Alkylidenecyclopentenones and 3‐Oxygenated 2‐Alkylideneindanones.
ChemInform·1988
Metal mediated routes to 5-membered rings
Pure and Applied Chemistry·1988· 38 citedOpen Access
A stereoselective, palladium-catalyzed route to 4-oxygenated 5-alkylidenecyclopentenones and 3-oxygenated 2-alkylideneindanones
Journal of the American Chemical Society·1987· 91 cited
Substituent effects on homolytic versus heterolytic photocleavage of (1-naphthylmethyl)trimethylammonium chlorides
Canadian Journal of Chemistry·1987· 18 cited
The preparation of aromatic amidino esters and their reaction with primary amines
Tetrahedron·1987· 15 cited
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Frequent Co-authors

Paul J. Reider(7), Paul N. Devine(7), R. P. Volante(5), Robert D. Larsen(4), F. E. ROBERTS(4), Thomas R. Verhoeven(4), David Mitchell(4), Lanny S. Liebeskind(4), Robert A. Reamer(3), David M. Tschaen(3), Edward J. J. Grabowski(3), G. Hughes(3), John R. Naber(3), Paul O’Shea(3), Daniel J. McKay(3), John T. Gupton(3), Anthony O. King(2), Edward G. Corley(2), David Lieberman(2), Lucius T. Rossano(2)