Christopher J. Thibodeaux

McGill University — Canada

Medicine · Health Sciences

18h-index2.1kcitations52works1.52yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(15), Carbohydrate Chemistry and Synthesis(8), Chemical Synthesis and Analysis(7), Plant biochemistry and biosynthesis(7), Biochemical and Molecular Research(7)

Publications52 total

A dynamic biointerface in mussels mediated by a mechanoresponsive intermediate filament-based biopolymer
Nature Communications·2025· 1 citedOpen Access
Inhibitor‐induced dimerization mediates lufotrelvir resistance in mutants of <scp>SARS</scp>‐<scp>CoV</scp>‐2 <scp>3C‐like protease</scp>
Protein Science·2025· 1 citedOpen Access
Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures
Nucleic Acids Research·2025Open Access
A focus on unexpected surprises in RiPP natural product biosynthesis
Chemical Science·2025Open Access
Defining the functional properties of cyclopropane fatty acid synthase from Pseudomonas aeruginosa PAO1
Journal of Biological Chemistry·2024· 5 citedOpen Access
Evaluation of Quatsome Morphology, Composition, and Stability for <i>Pseudomonas aeruginosa</i> Biofilm Eradication
Langmuir·2024· 2 cited
A naturally occurring <scp>G11S</scp> mutation in the <scp>3C</scp>‐like protease from the <scp>SARS‐CoV</scp>‐2 virus dramatically weakens the dimer interface
Protein Science·2023· 5 citedOpen Access
The conformationally dynamic structural biology of lanthipeptide biosynthesis
Current Opinion in Structural Biology·2023· 8 cited
A conserved SH3-like fold in diverse putative proteins tetramerizes into an oxidoreductase providing an antimicrobial resistance phenotype
Philosophical Transactions of the Royal Society B Biological Sciences·2023· 11 citedOpen Access
Purification, crystallization and crystallographic analysis of the PorX response regulator associated with the type IX secretion system
Acta Crystallographica Section F Structural Biology Communications·2022· 4 citedOpen Access
Exploring the Heterogeneous Structural Dynamics of Class II Lanthipeptide Synthetases with Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS)
Biochemistry·2022· 4 cited
Partially Modified Peptide Intermediates in Lanthipeptide Biosynthesis Alter the Structure and Dynamics of a Lanthipeptide Synthetase
Journal of the American Chemical Society·2022· 16 cited
574. High Acceptance and Rapid Implementation of COVID-19 Vaccine in a Public HIV Clinic in Northern California: An Initial Analysis of Social Determinants
Open Forum Infectious Diseases·2021· 2 citedOpen Access
Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reductase
Biochemistry·2021· 12 citedOpen Access
Biochemical and biophysical investigation of the HalM2 lanthipeptide synthetase using mass spectrometry
Canadian Journal of Chemistry·2021· 3 cited
Combining Small-Molecule Bioconjugation and Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS) to Expose Allostery: the Case of Human Cytochrome P450 3A4
ACS Chemical Biology·2021· 6 cited
Exploring the Conformational Landscape of a Lanthipeptide Synthetase Using Native Mass Spectrometry
Biochemistry·2021· 8 cited
Structural dynamics of cytochrome P450 3A4 in the presence of substrates and cytochrome P450 reductase
2021Open Access
Editors’ Choice—A Miniaturized Enzymatic Biosensor for Detection of Sensory-Evoked D-serine Release in the Brain
Journal of The Electrochemical Society·2021· 11 citedOpen Access
Mutations in Dynamic Structural Elements Alter the Kinetics and Fidelity of the Multifunctional Class II Lanthipeptide Synthetase, HalM2
Biochemistry·2021· 10 cited
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Frequent Co-authors

Hung‐wen Liu(19), Yeganeh Habibi(8), Kevin A. Uggowitzer(7), Charles E. Melançon(5), Wei‐chen Chang(5), Nuwani W. Weerasinghe(5), Wilfred A. van der Donk(4), Steven O. Mansoorabadi(4), Julie Ducharme(4), Karine Auclair(4), Nicolas Moitessier(3), Matthew J. Harrington(2), William Kittleman(2), Irina F. Sevrioukova(2), Janine Mauzeroll(2), Annie R. Q. Shao(2), Felipe A. Venegas(2), Guanyu Wang(2), Andrés M. Rueda(2), Anthony Mittermaier(2)