Jonathan D. Worboys

Manchester Academic Health Science Centre — United Kingdom

Immunology and Microbiology · Life Sciences

13h-index1.4kcitations22works2.02yr avg
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Research Topics

Immune Cell Function and Interaction(4), T-cell and B-cell Immunology(3), Advanced Proteomics Techniques and Applications(3), Inflammasome and immune disorders(3), Immune cells in cancer(3)

Publications22 total

CD155 density on target cells drives divergent natural killer cell responses owing to DNAM-1 loss
The Journal of Immunology·2025Open Access
Nano-org, a functional resource for single-molecule localisation microscopy data
Nature Communications·2025· 2 citedOpen Access
Inhibitory TIGIT signalling is dependent on T cell receptor activation
2025Open Access
CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity
Frontiers in Immunology·2025· 3 citedOpen Access
Do inhibitory receptors need to be proximal to stimulatory receptors to function?
Genes and Immunity·2024· 5 citedOpen Access
TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
Nature Communications·2023· 51 citedOpen Access
Method to Measure Ubiquitination of NLRs
Methods in molecular biology·2023
Heterogeneity in extracellular vesicle secretion by single human macrophages revealed by super‐resolution microscopy
Journal of Extracellular Vesicles·2022· 46 citedOpen Access
Internalization of the Membrane Attack Complex Triggers NLRP3 Inflammasome Activation and IL-1β Secretion in Human Macrophages
Frontiers in Immunology·2021· 27 citedOpen Access
Synaptic secretion from human natural killer cells is diverse and includes supramolecular attack particles
Proceedings of the National Academy of Sciences·2020· 61 citedOpen Access
Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing
Blood Advances·2020· 211 citedOpen Access
USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
EMBO Reports·2018· 172 citedOpen Access
Abstract A34: Oncogenic KRAS regulates pancreatic cancer cell signaling via stromal reciprocation
Cancer Research·2016· 1 cited
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
Cell·2016· 79 citedOpen Access
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
Cell·2016· 370 citedOpen Access
Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration
Science Signaling·2016· 44 cited
Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis
eLife·2016· 182 citedOpen Access
Author response: Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis
2016Open Access
Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC.
PubMed·2014· 3 citedOpen Access
Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO<sub>2</sub> and Ti-IMAC
Analytical Chemistry·2014· 91 citedOpen Access
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Frequent Co-authors

Claus Jørgensen(10), Daniel M. Davis(10), Christopher J. Tape(6), Douglas A. Lauffenburger(6), Kelly McMahon(5), Ida C. Norrie(4), Ashley Ambrose(4), Stephanie Ling(3), Maria Dimitriadi(3), Hui Sun Leong(3), Crispin Miller(3), George Poulogiannis(3), Gloria López‐Castejón(3), John Sinclair(3), Khodor S. Hazime(3), Gillian M. Tannahill(3), Kevin Stacey(2), Faraz K. Mardakheh(2), Afshan McCarthy(2), Maggie Yeo(2)