Anna‐Sophia Wiekmeijer

Galapagos (Netherlands) — Netherlands

Medicine · Health Sciences

9h-index639citations26works1.02yr avg
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Research Topics

CAR-T cell therapy research(10), Immune Cell Function and Interaction(7), Immunotherapy and Immune Responses(6), T-cell and B-cell Immunology(4), Virus-based gene therapy research(4)

Publications26 total

Randomized clinical efficacy and safety study of peltopepimut-S plus cemiplimab compared to cemiplimab alone in patients with recurrent/metastatic HPV16-positive head and neck cancer
Journal for ImmunoTherapy of Cancer·2025· 2 citedOpen Access
THU-269 Interim results of a phase I/II study to determine the safety, immunogenicity and efficacy of therapeutic hepatitis B virus synthetic long peptide vaccination
Journal of Hepatology·2025
Induction of broad multifunctional CD8+ and CD4+ T cells by hepatitis B virus antigen-based synthetic long peptides ex vivo
Frontiers in Immunology·2023· 9 citedOpen Access
Enhanced HPV16 E6/E7+ tumor eradication via induction of tumor-specific T cells by therapeutic vaccination with virosomes presenting synthetic long peptides
Cancer Immunology Immunotherapy·2023· 10 citedOpen Access
Combination immunotherapy with synthetic long peptides and chemotherapy or PD-1 blocker for cancers caused by human papilloma virus type 16
Seminars in Immunopathology·2023· 5 cited
1181 Therapeutic vaccines consisting of cancer germline antigen-based synthetic long peptides are immunogenic in human hepatocellular carcinoma patients
Regular and Young Investigator Award Abstracts·2022Open Access
A unique immune signature in blood separates therapy-refractory from therapy-responsive acute graft-versus-host disease
Blood·2022· 8 citedOpen Access
Therapeutic cancer vaccines targeting viral antigens
Elsevier eBooks·2022
List of contributors
Elsevier eBooks·2022
The Development of T Cells From Stem Cells in Mice and Humans
Future Science OA·2017· 73 citedOpen Access
In vivo modelling of normal and pathological human T-cell development
Leiden Repository (Leiden University)·2016Open Access
Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms
Experimental Hematology·2016· 12 cited
The functional relationship between hematopoietic stem cells and developing T lymphocytes
Annals of the New York Academy of Sciences·2016· 8 cited
Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus
Proceedings of the National Academy of Sciences·2015· 38 citedOpen Access
Identification of checkpoints in human T-cell development using severe combined immunodeficiency stem cells
Journal of Allergy and Clinical Immunology·2015· 28 citedOpen Access
Transplantation of human SCID stem cells in NSG mice gives new insights into human T-cell development
Data Archiving and Networked Services (DANS)·2015
The composition and differentiation potential of the duodenal intraepithelial innate lymphocyte compartment is altered in coeliac disease
Gut·2015· 29 citedOpen Access
Development of a diverse human T cell repertoire despite severe restriction of hematopoietic clonality in the thymus
Data Archiving and Networked Services (DANS)·2014
Transplantation of human SCID stem cells in NSG mice gives new insights into human T-cell development and reveals where SCID mutations act
Data Archiving and Networked Services (DANS)·2014
Sustained Engraftment of Cryopreserved Human Bone Marrow CD34 <sup>+</sup> Cells in Young Adult NSG Mice
BioResearch open access·2014· 35 citedOpen Access
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Frequent Co-authors

Frank J. T. Staal(16), Karin Pike‐Overzet(12), Martijn H. Brugman(10), Cornelis J.M. Melief(8), Anton W. Langerak(6), Willem E. Fibbe(5), Robbert G. M. Bredius(5), Jacques J. M. van Dongen(5), Jules P.P. Meijerink(4), Irene Homminga(3), Rob Pieters(3), Andrew Stubbs(3), Monique M.A. Verstegen(3), Maartje Vuerhard(3), Jessica G. C. A. M. Buijs-Gladdines(3), Clarissa Kooi(3), Petra Klous(3), Adolfo A. Ferrando(3), Brenda Verhaaf(3), Martin A. Horstmann(3)