Sungyun Cho

Cornell University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index1.4kcitations40works12.52yr avg
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Research Topics

RNA modifications and cancer(6), Cholesterol and Lipid Metabolism(6), Cancer, Hypoxia, and Metabolism(5), PI3K/AKT/mTOR signaling in cancer(5), RNA Research and Splicing(4)

Publications40 total

FAP PET identifies earlycardiac molecular changesinduced by doxorubicin chemotherapy
JCI Insight·2025Open Access
Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling
Science·2025· 25 cited
β-Ionone suppresses colorectal tumorigenesis by activating OR51E2, a potential tumor suppressor
Phytomedicine·2025· 1 citedOpen Access
SIRT6 Ameliorates Cancer Cachexia–Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice
Journal of Cachexia Sarcopenia and Muscle·2025· 5 citedOpen Access
mTORC1, the maestro of cell metabolism and growth
Genes & Development·2024· 30 citedOpen Access
Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing
Molecular Cell·2024· 14 citedOpen Access
PET imaging of fibroblast activation protein alpha (FAP) detects incipient cardiotoxicity due to anthracycline chemotherapy
2023· 1 citedOpen Access
FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
Molecular Cell·2023· 26 citedOpen Access
Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat diet
Aging Cell·2022· 30 citedOpen Access
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression
Nature Communications·2022· 60 citedOpen Access
Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells
Science Advances·2022· 45 citedOpen Access
Tumor-produced aging-associated oncometabolite, methylmalonic acid, promotes cancer-associated fibroblast activation to drive metastatic progression
2022Open Access
mTORC1 promotes cell growth via m6A-dependent mRNA degradation
Molecular Cell·2021· 113 citedOpen Access
mTORC1-chaperonin CCT signaling regulates m <sup>6</sup> A RNA methylation to suppress autophagy
Proceedings of the National Academy of Sciences·2021· 70 citedOpen Access
Abstract IA12: Coordination of mRNA processing, translation, and metabolism by mTORC1
Molecular Cancer Research·2020
Abstract PR05: Regulation of mRNA N6-adenosine methylation by the mTOR signaling
Molecular Cancer Research·2020
Development of Digital Signage Modules composed of Mini-LEDs using Laser-Assisted Bonding (LAB) Technology
2020· 11 cited
Corrigendum to “Activation of AMP‐Activated Protein Kinase and Extracelluar Signal‐Regulated Kinase Mediates CB‐PIC‐Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells”
Evidence-based Complementary and Alternative Medicine·2020Open Access
mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation
Molecular Cell·2018· 143 citedOpen Access
Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling
Cell·2017· 205 citedOpen Access
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Frequent Co-authors

John Blenis(13), Gina Lee(7), Long He(7), Zhongchi Li(7), Cholsoon Jang(5), Noah Dephoure(5), Sung‐Joon Lee(5), Hyo‐Jeong Lee(5), Joshua D. Rabinowitz(4), Lewis C. Cantley(4), Heejin Jun(4), Vivien Low(4), Bonglee Kim(4), John M. Asara(3), Mi Ja Chung(3), Kyoung Heon Kim(3), Hyo‐Jung Lee(3), Sung‐Hoon Kim(3), Jennifer E. Endress(3), Eun Jung Sohn(3)