Robert V. Farese

Memorial Sloan Kettering Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

110h-index48.0kcitations312works5.62yr avg
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Research Topics

Lipid metabolism and biosynthesis(138), Adipose Tissue and Metabolism(94), Pancreatic function and diabetes(54), Photosynthetic Processes and Mechanisms(32), Amyotrophic Lateral Sclerosis Research(31)

Publications308 total

Proteome Landscapes Decode Organelle Vulnerabilities in cortical and dopaminergic-like induced neurons Across Lysosomal Storage Disorders
2025· 1 citedOpen Access
The pathogenesis of hepatic steatosis in MASLD: a lipid droplet perspective
Journal of Clinical Investigation·2025· 4 citedOpen Access
Plasma lipidome dysregulation in frontotemporal dementia reveals shared, genotype‐specific, and severity‐linked alterations
Alzheimer s & Dementia·2025· 1 citedOpen Access
Mechanism for oil-phase separation by the lipid droplet assembly complex
2025· 1 citedOpen Access
The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway
Immunity·2025· 10 citedOpen Access
Abstract 2716 Lipid degradation
Journal of Biological Chemistry·2025Open Access
Plasma lipidome dysregulation in frontotemporal dementia reveals shared, genotype-specific, and severity-linked alterations
2025Open Access
Essential Biology of Lipid Droplets
Annual Review of Biochemistry·2025· 14 citedOpen Access
ỨNG DỤNG TRÍ TUỆ NHÂN TẠO CÁ NHÂN HÓA HOẠT ĐỘNG HỌC TẬP CỦA SINH VIÊN
Tạp chí Khoa học·2025Open Access
A progranulin variant causing childhood interstitial lung disease responsive to anti-TNF-α biologic therapy
Med·2025Open Access
DHRS7 Integrates NADP <sup>+</sup> /NADPH Redox Sensing with Inflammatory Lipid Signalling via the Oxoeicosanoid Pathway
2025· 4 citedOpen Access
Partial loss of <i>FITM2</i> function causes hereditary spastic paraplegia
2025Open Access
Correction: Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core
Journal of Biological Chemistry·2024· 1 citedOpen Access
PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes
Cell·2024· 42 citedOpen Access
Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia
2024· 2 citedOpen Access
Organelle bridges and nanodomain partitioning govern targeting of membrane-embedded proteins to lipid droplets
2024· 9 citedOpen Access
PLD3 and PLD4 synthesize <i>S,S</i> -BMP, a key phospholipid enabling lipid degradation in lysosomes
2024· 6 citedOpen Access
Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity
eLife·2023· 3 citedOpen Access
Author Response: Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity
2023Open Access
Author Response: Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity
2023Open Access
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Frequent Co-authors

Tobias C. Walther(21), Sylvaine Cases(5), Scot J. Stone(5), Steven J. Smith(4), Heather Myers(4), Florian Wilfling(4), Joel T. Haas(4), Matthew D. Hirschey(3), Bjoern Schwer(3), Carrie A. Grueter(3), Charles Harris(3), Robert D. Stevens(3), Christopher B. Newgard(3), Frederick W. Alt(3), Eric Verdin(3), Eric Sande(3), Sabine Novak(3), Abdou Rachid Thiam(3), Robert H. Eckel(3), Natalie Krahmer(3)