Farshid N. Rouhani

Spitalul Clinic Colentina — Romania

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index3.2kcitations58works0.02yr avg
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Research Topics

Protease and Inhibitor Mechanisms(12), Peptidase Inhibition and Analysis(12), Virus-based gene therapy research(9), Blood Coagulation and Thrombosis Mechanisms(7), Viral Infectious Diseases and Gene Expression in Insects(6)

Publications58 total

Impact of intravenous azithromycin on endoscopic preparation in acute upper gastrointestinal bleeding: Preliminary results from the CLEAN-AZ Study
Endoscopy·2025
Ablate, stent and repeat: Feasibility, clinical success and safety profile of intraductal radiofrequency ablation in the management of inoperable perihilar cholangiocarcinoma patients – interim analysis of the COMBO-RFA randomized clinical trial
Endoscopy·2024
Post-liver Transplant Inferior Vena Cava Stenosis in a Large Volume UK Centre
HPB·2021
5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency
Molecular Therapy·2017· 105 citedOpen Access
Alpha-1 Antitrypsin PiMZ Genotype Is Associated with Chronic Obstructive Pulmonary Disease in Two Racial Groups
Annals of the American Thoracic Society·2017· 77 citedOpen Access
Alpha-1 Antitrypsin-Deficient Macrophages Have Increased Matriptase-Mediated Proteolytic Activity
American Journal of Respiratory Cell and Molecular Biology·2017· 23 citedOpen Access
SVIP regulates Z variant alpha-1 antitrypsin retro-translocation by inhibiting ubiquitin ligase gp78
PLoS ONE·2017· 17 citedOpen Access
24. Sustained Expression with Partial Correction of Neutrophil Defects 5 Years After Intramuscular rAAV1 Gene Therapy for Alpha-1 Antitrypsin Deficiency
Molecular Therapy·2016· 2 citedOpen Access
human airway epithelial (NCI-H292) cells Proteasome inhibition induces TNFR1 shedding from
2016
United States Targeted Detection Program for Alpha-1 Antitrypsin Deficiency
Respiratory medicine·2015· 2 cited
Parallel 20: Pediatric and Metabolic Liver Diseases: Clinical
Hepatology·2015Open Access
Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody
The International Journal of Biochemistry & Cell Biology·2014· 29 citedOpen Access
Longer Telomere Length in COPD Patients with α1-Antitrypsin Deficiency Independent of Lung Function
PLoS ONE·2014· 29 citedOpen Access
Circulating polymers in α<sub>1</sub>-antitrypsin deficiency
European Respiratory Journal·2014· 86 citedOpen Access
Genome-Wide Study of Percent Emphysema on Computed Tomography in the General Population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study
American Journal of Respiratory and Critical Care Medicine·2014· 102 cited
Human Treg responses allow sustained recombinant adeno-associated virus–mediated transgene expression
Journal of Clinical Investigation·2013· 158 citedOpen Access
Biochemical Efficacy and Safety of a New, Ready-to-Use, Liquid Alpha-1-Proteinase Inhibitor, GLASSIA (Alpha<sub>1</sub>-Proteinase Inhibitor (Human), Intravenous)
COPD Journal of Chronic Obstructive Pulmonary Disease·2013· 19 cited
Alpha-1 Antitrypsin Augmentation Therapy and Biomarkers of Elastin Degradation
COPD Journal of Chronic Obstructive Pulmonary Disease·2013· 47 citedOpen Access
Cytosolic, Autocrine Alpha-1 Proteinase Inhibitor (A1PI) Inhibits Caspase-1 and Blocks IL-1β Dependent Cytokine Release in Monocytes
PLoS ONE·2012· 14 citedOpen Access
Development, validation and use of ELISA for antibodies to human alpha-1 antitrypsin
Journal of Immunological Methods·2012· 6 cited
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Frequent Co-authors

Mark Brantly(30), Stewart J. Levine(16), Xinle Cui(11), Feras Hawari(10), Jeffrey D. Chulay(7), Terence R. Flotte(6), Margaret Humphries(6), Robert A. Sandhaus(6), Noel G. McElvaney(6), James M. Wilson(6), Barbara Adamik(6), Roberto Calcedo(5), Martha Campbell‐Thompson(5), Christian Mueller(5), Feras Hawari(5), Aminul Islam(5), Jing Zhang(5), Anthony T. Yachnis(4), Maryann Kaler(4), Bruce C. Trapnell(3)