Fredrick R. Nelson

Pfizer (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

3h-index371citations5works0.02yr avg
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Research Topics

Phosphodiesterase function and regulation(4), Cholinesterase and Neurodegenerative Diseases(3), Receptor Mechanisms and Signaling(2), Psychopathy, Forensic Psychiatry, Sexual Offending(1), Neuroinflammation and Neurodegeneration Mechanisms(1)

Publications5 total

Phosphodiesterase 9A Regulates Central cGMP and Modulates Responses to Cholinergic and Monoaminergic Perturbation In Vivo
Journal of Pharmacology and Experimental Therapeutics·2012· 79 cited
A non-brain penetrant PDE5A inhibitor improves functional recovery after stroke in rats
Restorative Neurology and Neuroscience·2012· 7 cited
Utilizing structure-based design to discover a potent, selective, in vivo active PDE10A inhibitor lead series for the treatment of schizophrenia
Abstracts of papers - American Chemical Society·2009
Preclinical Characterization of Selective Phosphodiesterase 10A Inhibitors: A New Therapeutic Approach to the Treatment of Schizophrenia
Journal of Pharmacology and Experimental Therapeutics·2008· 284 cited
The forensic psychology section in a state hospital.
Professional Psychology·1978· 1 cited

Frequent Co-authors

Frank S. Menniti(4), Douglas S. Chapin(3), J. Cianfrogna(2), Mihály Hajós(2), John F. Harms(2), Lorraine A. Lebel(2), Mark J. Majchrzak(2), Karl T. Schmidt(2), Judith A. Siuciak(2), F. David Tingley(2), Robert D. Williams(2), Patrick R. Verhoest(2), Christopher J. Helal(2), Diane Stephenson(2), Robert W. Wildman(2), C J Schmidt(1), Michael L. Corman(1), William E. Hoffman(1), Sheryl A. McCarthy(1), Caroline Proulx-LaFrance(1)