Elke Will

Cincinnati Children's Hospital Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index980citations16works0.02yr avg
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Research Topics

Virus-based gene therapy research(8), CRISPR and Genetic Engineering(6), Cellular transport and secretion(4), Endoplasmic Reticulum Stress and Disease(4), Mesenchymal stem cell research(3)

Publications16 total

Importance of Murine Study Design for Testing Toxicity of Retroviral Vectors in Support of Phase I Trials
Molecular Therapy·2007· 25 citedOpen Access
Lentiviral vectors pseudotyped with murine ecotropic envelope: Increased biosafety and convenience in preclinical research
Experimental Hematology·2006· 108 cited
457. Reverse Transcriptase Deficient Retroviral Vectors for Transient Cell Modification
Molecular Therapy·2006Open Access
459. Murine Study To Evaluate Long-Term Transgene Expression of the MSCV-MGMTP140K wc Retroviral Vector in Support of a Phase I Gene Transfer Trial-Limitations of the Murine Model as a Pre-Clinical Tool
Molecular Therapy·2006Open Access
HOXB4 Inhibits Cell Growth in a Dose-Dependent Manner and Sensitizes Cells Towards Extrinsic Cues
Cell Cycle·2005· 21 citedOpen Access
Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine–DNA methyltransferase in hematopoietic cells
Molecular Therapy·2005· 196 citedOpen Access
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells
Proceedings of the National Academy of Sciences·2005· 83 citedOpen Access
HOXB4 Enforces Equivalent Fates of ES-Cell-Derived and Adult Hematopoietic Cells.
Blood·2004· 3 cited
Retroviral Pseudotransduction for Targeted Cell Manipulation
Molecular Cell·2004· 78 citedOpen Access
Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose
Experimental Hematology·2003· 61 cited
High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation
Blood·2003· 155 citedOpen Access
Posttranslational Modification of Serine to Formylglycine in Bacterial Sulfatases
Journal of Biological Chemistry·2003· 51 citedOpen Access
Biochemical Characterization of Gyp6p, a Ypt/Rab-specific GTPase-activating Protein from Yeast
Journal of Biological Chemistry·2001· 51 citedOpen Access
[6] Expression, purification, and biochemical properties of Ypt/Rab GTPase-activating proteins of Gyp family
Methods in enzymology on CD-ROM/Methods in enzymology·2001· 8 cited
Primary structure and biochemical characterization of yeast 
GTPase‐activating proteins with substrate preference for the transport GTPase Ypt7p
European Journal of Biochemistry·1999· 60 cited
Structural and Functional Analysis of a Novel Coiled-Coil Protein Involved in Ypt6 GTPase-regulated Protein Transport in Yeast
Molecular Biology of the Cell·1999· 80 citedOpen Access

Frequent Co-authors

Christopher Baum(9), David A. Williams(5), Ute Modlich(5), Bernhard Schiedlmeier(4), Hannes Klump(4), Dieter Gallwitz(4), Axel Schambach(3), Melanie Galla(3), Lilith Reeves(3), Saurabh Chandra(2), Christopher Baum(2), Zheng Wang(2), Andreas Rimek(2), Wolfram Ostertag(2), Christof von Kalle(2), Sandra Pilat(2), Sebastian Carotta(2), Andreas Mairhofer(2), Peter Steinlein(2), Janine Kraunus(2)