Bernhard Schiedlmeier

Medizinische Hochschule Hannover — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.7kcitations51works0.02yr avg
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Research Topics

Virus-based gene therapy research(25), RNA Interference and Gene Delivery(12), CRISPR and Genetic Engineering(12), CAR-T cell therapy research(10), Pluripotent Stem Cells Research(9)

Publications48 total

Genetic Regulation of Fate Decisions in Therapeutic T Cells to Enhance Tumor Protection and Memory Formation (vol 75, pg 2641, 2015)
UCL Discovery (University College London)·2015
Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells
Stem Cells Translational Medicine·2015· 25 citedOpen Access
Tightly regulated ‘all-in-one’ lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy
Gene Therapy·2015· 8 citedOpen Access
Genetic Regulation of Fate Decisions in Therapeutic T Cells to Enhance Tumor Protection and Memory Formation
Cancer Research·2015· 24 cited
Inducible T-cell receptor expression in precursor T cells for leukemia control
Leukemia·2015· 10 citedOpen Access
Timely Controlled T Cell Receptor Expression of Genetically Engineered Precursor T Cells Requires Early Transgene Induction for Leukemia Control after Hematopoietic Stem Cell Transplantation
Blood·2014
Generation of iPSCs from Genetically Corrected <i>Brca2</i> Hypomorphic Cells: Implications in Cell Reprogramming and Stem Cell Therapy
Stem Cells·2013· 15 citedOpen Access
Serum- and Stromal Cell-Free Hypoxic Generation of Embryonic Stem Cell-Derived Hematopoietic Cells In Vitro, Capable of Multilineage Repopulation of Immunocompetent Mice
Stem Cells Translational Medicine·2012· 18 citedOpen Access
Angptl4 maintains <i>in vivo</i> repopulation capacity of <scp>CD</scp>34<sup>+</sup> human cord blood cells
European Journal Of Haematology·2012· 13 citedOpen Access
Polyclonal fluctuation of lentiviral vector–transduced and expanded murine hematopoietic stem cells
Blood·2011· 56 citedOpen Access
Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges
Journal of Molecular Biology·2011· 169 cited
Cell and Virus Genetics at the Roots of Gene Therapy, Retrovirology, and Hematopoietic Stem Cell Biology: Wolfram Ostertag (1937–2010)
Human Gene Therapy·2010· 1 cited
Retroviral and Transposon-Based Tet-Regulated All-In-One Vectors with Reduced Background Expression and Improved Dynamic Range
Human Gene Therapy·2010· 101 cited
Cell-intrinsic and Vector-related Properties Cooperate to Determine the Incidence and Consequences of Insertional Mutagenesis
Molecular Therapy·2009· 65 citedOpen Access
From birth to adulthood in a nutshell : hematopoietic stem cell development in vitro &amp; HOXB4
The FASEB Journal·2009
Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-α on Fanconi anemia hematopoietic stem and progenitor cells
Blood·2009· 27 citedOpen Access
Murine Hematopoietic Stem Cell Transduction Using Retroviral Vectors
Methods in molecular biology·2009· 10 cited
Ectopic HOXB4 Overcomes the Inhibitory Effect of TNFα on Hematopoietic Stem and Progenitor Cells in a Murine Fanconi Anemia Model.
Blood·2008
Cell-Intrinsic Heterogeneity Plays An Important Role in the Development of Clonal Dominance after Retroviral Gene Transfer into Hematopoietic Stem Cells
Blood·2008
Too little, too late: The initial experience in FA gene therapy
Blood Cells Molecules and Diseases·2008
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Frequent Co-authors

Christopher Baum(16), Hannes Klump(13), Axel Schambach(11), Niels Heinz(11), Wolfram Ostertag(9), Stefan Früehauf(9), Ute Modlich(8), W. Jens Zeller(7), Klaus Kühlcke(6), Melanie Galla(5), David A. Williams(5), Jutta Friel(5), C Baum(5), Olga Kustikova(5), Zhixiong Li(5), Elke Will(4), Sandra Pilat(4), Sebastian Carotta(4), Kenji Kamino(4), Boris Fehse(4)