Sean R. A. Devenish

German Center for Neurodegenerative Diseases — Germany

Materials Science · Physical Sciences

20h-index1.6kcitations59works7.02yr avg
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Research Topics

Enzyme Structure and Function(18), Biochemical and Molecular Research(13), Microfluidic and Capillary Electrophoresis Applications(12), SARS-CoV-2 and COVID-19 Research(10), Innovative Microfluidic and Catalytic Techniques Innovation(9)

Publications59 total

Serological Markers of Clinical Improvement in MuSK Myasthenia Gravis
Neurology Neuroimmunology & Neuroinflammation·2024· 8 citedOpen Access
α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes
ACS Nano·2024· 12 citedOpen Access
Microfluidic Diffusional Sizing (MDS) Measurements of Secretory Neutralizing Antibody Affinity Against SARS-CoV-2
Annals of Biomedical Engineering·2024· 1 citedOpen Access
Rapid quantitative assessment of small molecule leakage from microdroplets by flow cytometry and improvement of fluorophore retention in biochemical assays
2023· 8 citedOpen Access
α-synuclein oligomers displace monomeric α-synuclein from lipid membranes
2023· 4 citedOpen Access
Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling
STAR Protocols·2023· 7 citedOpen Access
FULL-MDS: Fluorescent Universal Lipid Labeling for Microfluidic Diffusional Sizing
Analytical Chemistry·2022· 7 citedOpen Access
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
Scientific Reports·2022· 5 citedOpen Access
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
iScience·2022· 20 citedOpen Access
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
2022Open Access
Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2
ACS Infectious Diseases·2022· 10 citedOpen Access
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
2022· 5 citedOpen Access
Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape
2021· 1 citedOpen Access
Understanding the role of memory re-activation and cross-reactivity in the defense against SARS-CoV-2
2021· 4 citedOpen Access
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum
ACS Infectious Diseases·2021· 43 cited
Rapid highly sensitive general protein quantification through on-chip chemiluminescence
Biomicrofluidics·2021· 3 citedOpen Access
Machine learning-aided protein identification from multidimensional signatures
Lab on a Chip·2021· 8 citedOpen Access
In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
2020· 5 citedOpen Access
Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies
Nature Structural & Molecular Biology·2020· 187 cited
Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
2020· 16 citedOpen Access
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Frequent Co-authors

Tuomas P. J. Knowles(17), Juliet A. Gerrard(15), Sebastian Fiedler(13), Florian Hollfelder(9), Georg Meisl(9), Renwick C. J. Dobson(9), Alexey S. Morgunov(9), Alison Ilsley(9), Adriano Aguzzi(9), Catherine K. Xu(8), Matthias M. Schneider(7), Vasilis Kosmoliaptsis(7), Heike Fiegler(7), F. Grant Pearce(6), Geoffrey B. Jameson(6), Kadi L. Saar(6), Anisa Y. Malik(6), Marc Emmenegger(6), Monika A. Piziorska(5), Viola Denninger(5)