Jessika C. Zevenhoven-Dobbe

Leiden University Medical Center — Netherlands

Agricultural and Biological Sciences · Life Sciences

25h-index6.8kcitations37works4.02yr avg
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Research Topics

Animal Virus Infections Studies(29), Viral gastroenteritis research and epidemiology(23), SARS-CoV-2 and COVID-19 Research(19), Viral Infections and Immunology Research(11), Virus-based gene therapy research(8)

Publications37 total

Bivalent mRNA vaccine booster enhances immunity against XBB.1.5 more effectively than breakthrough infection in K18-hACE2 mice
iScience·2025Open Access
Characterization of SARS-CoV-2 replication in human H1299/ACE2 cells: A versatile and practical infection model for antiviral research and beyond
Antiviral Research·2024· 8 citedOpen Access
Structure–function analysis of the nsp14 N7–guanine methyltransferase reveals an essential role in <i>Betacoronavirus</i> replication
Proceedings of the National Academy of Sciences·2021· 54 citedOpen Access
6′,6′-Difluoro-aristeromycin is a potent inhibitor of MERS-coronavirus replication
2021· 1 citedOpen Access
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in <i>Betacoronavirus</i> replication
2021Open Access
The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2
Journal of Virology·2020· 295 citedOpen Access
Coronavirus discovery by metagenomic sequencing: a tool for pandemic preparedness
Journal of Clinical Virology·2020· 44 citedOpen Access
A molecular pore spans the double membrane of the coronavirus replication organelle
Science·2020· 534 citedOpen Access
A molecular pore spans the double membrane of the coronavirus replication organelle
2020· 52 citedOpen Access
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
Journal of General Virology·2020· 627 citedOpen Access
The enzymatic activity of the nsp14 exoribonuclease is critical for replication of Middle East respiratory syndrome-coronavirus
2020· 7 citedOpen Access
A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis
PLoS Biology·2020· 466 citedOpen Access
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
2020· 70 citedOpen Access
A unifying structural and functional model of the coronavirus replication organelle: tracking down RNA synthesis
2020· 100 citedOpen Access
Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture
Virology·2017· 25 citedOpen Access
Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model
Virus Research·2016· 84 citedOpen Access
Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses
Nucleic Acids Research·2015· 245 citedOpen Access
Arterivirus nsp12 versus the coronavirus nsp16 2′-O-methyltransferase: comparison of the C-terminal cleavage products of two nidovirus pp1ab polyproteins
Journal of General Virology·2015· 29 citedOpen Access
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
Proceedings of the National Academy of Sciences·2014· 630 citedOpen Access
Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
Antimicrobial Agents and Chemotherapy·2014· 746 citedOpen Access
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Frequent Co-authors

Eric J. Snijder(35), Clara C. Posthuma(16), Yvonne van der Meer(8), Natacha S. Ogando(7), Adriaan H. de Wilde(6), Alexander E. Gorbalenya(6), Ronald W.A.L. Limpens(6), Montserrat Bárcena(6), Abraham J. Koster(5), Igor A. Sidorov(5), Bruno Canard(4), Jutte J.C. de Vries(4), Anja W. M. de Jong(4), Marjolein Kikkert(3), A. Mieke Mommaas(3), Étienne Decroly(3), Volker Thiel(3), Corrine Beugeling(3), Kèvin Knoops(2), Sjoerd H. E. van den Worm(2)