Sung-Sau So

Schrodinger (United States) — United States

Computer Science · Physical Sciences

5h-index355citations10works0.02yr avg
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Research Topics

Computational Drug Discovery Methods(2), Pharmacogenetics and Drug Metabolism(2), Cancer-related Molecular Pathways(2), Protein Degradation and Inhibitors(2), Cancer Mechanisms and Therapy(2)

Publications10 total

Structurally Enabling ADMET Anti-Targets via Induced Fit Docking and Free Energy Perturbation
2026Open Access
Structurally Enabling ADMET Anti-Targets via Induced Fit Docking and Free Energy Perturbation
2026Open Access
Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia
Journal of Medicinal Chemistry·2014· 204 citedOpen Access
Potent MCH-1 receptor antagonists from cis-1,4-diaminocyclohexane-derived indane analogs
Bioorganic & Medicinal Chemistry Letters·2013· 14 citedOpen Access
Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity
Journal of Medicinal Chemistry·2006· 116 citedOpen Access
Design, synthesis of 1,4-cyclohexyldiamine substituted diaminopyrimidines as selective inhibitors of CDK1, CDK2 and CDK4 and their in vitro and in vivo evaluation
Cancer Research·2005· 1 cited
AN IN VITRO RNA AMPLIFICATION STRATEGY ALLOWS CDNA MICROARRAY ANALYSIS OF SMALL AMOUNTS OF TISSUE
Transplantation·1998
Cyclosporine and tacrolimus both suppress activation of Kupffer cells in vitro.
PubMed·1996· 7 cited
In vitro immunosuppressive effects of murine hepatocyte cytosol.
PubMed·1989· 2 cited
The presence of cytotoxic autoantibody to lacrimal gland cells in NZB/W mice.
PubMed·1985· 10 cited

Frequent Co-authors

Karin Conde‐Knape(2), Yimin Qian(2), Jefferson Tilley(2), Xin‐Jie Chu(2), Wanda DePinto(2), Binh Thanh Vu(2), Kathryn Packman(2), Christine Lukacs(2), Qingjie Ding(2), Nan Jiang(2), Xuefeng Yin(2), Yingsi Chen(2), John Moliterni(2), Gerald L. Kaplan(2), Bradford Graves(2), Allen Lovey(2), Carlos O. Esquivel(2), Howook Hwang(2), Mee Shelley(2), Andrew Placzek(2)