Klaus Hansen

University of Copenhagen — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index9.6kcitations87works0.02yr avg
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Research Topics

Epigenetics and DNA Methylation(32), Genomics and Chromatin Dynamics(17), Cancer-related gene regulation(13), RNA modifications and cancer(9), Ubiquitin and proteasome pathways(8)

Publications87 total

Corrigendum: The Polycomb group proteins bind throughout the<i>INK4A-ARF</i>locus and are disassociated in senescent cells
Genes & Development·2023· 5 citedOpen Access
The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters
Genome Research·2023· 22 citedOpen Access
BIOM-37. ELUCIDATION OF THE TRANSCRIPTOMIC CONSEQUENCES OF KLF4 AND TRAF7 MUTATIONS IN SECRETORY MENINGIOMAS
Neuro-Oncology·2021Open Access
KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
Nature Cell Biology·2020· 119 citedOpen Access
User-Friendly and Interactive Analysis of ChIP-Seq Data Using EaSeq
Methods in molecular biology·2020· 14 cited
Going low to reach high: Small‐scale ChIP‐seq maps new terrain
WIREs Systems Biology and Medicine·2019· 12 cited
<i>N</i> 6-methyladenosine dynamics during early vertebrate embryogenesis
2019· 4 citedOpen Access
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
eLife·2019· 51 citedOpen Access
Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion
Oncogene·2019· 21 cited
Author response: PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
2018Open Access
Author response: PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
2018Open Access
Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer
Clinical Cancer Research·2018· 84 cited
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
Nature Communications·2018· 96 citedOpen Access
A histone H4K20 methylation-mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
2018Open Access
Quantitative Assessment of Drug Delivery to Tissues and Association with Phospholipidosis: A Case Study with Two Structurally Related Diamines in Development
Molecular Pharmaceutics·2017· 20 cited
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia
Nature Medicine·2016· 252 citedOpen Access
A High-Density Map for Navigating the Human Polycomb Complexome
Cell Reports·2016· 301 citedOpen Access
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
Nature·2016· 644 citedOpen Access
A High Density Map for Navigating the Human Polycomb Complexome
2016· 22 citedOpen Access
A novel epigenetic resistance mechanism to the FLT3 inhibitor PK412 induces cross-resistance to standard chemotherapy in acute myeloid leukemia (AML).
Max Planck Digital Library·2016
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Frequent Co-authors

Kristian Helin(15), Mads Lerdrup(13), Nikolaj Dietrich(8), Shuchi Agrawal‐Singh(8), Adrian P. Bracken(6), Diego Pasini(6), Juri Rappsilber(5), Paul A. Cloos(4), Karl Agger(4), Jens Vilstrup Johansen(4), Carl‐Henrik Heldin(4), Lars Rönnstrand(4), Jesper Frank Christensen(3), Jiří Lukáš(3), Jiří Bártek(3), Hans‐Ulrich Klein(3), Martin Dugas(3), Wolfgang E. Berdel(3), Carsten Müller‐Tidow(3), Erik Södersten(3)